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108219 Tris(hydroksymetylo)aminometan, chlorowodorek

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Tris(hydroksymetylo)aminometan, chlorowodorek MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Trometamol, Aminomethylidine trimethanol, 2-Amino-2-hydroxymethyl-1.3-propanediol, TRIS-buffer

CAS #: 1185-53-1 EC Number: 214-684-5 Molar Mass: 157.60 g/mol Chemical Formula: C₄H₁₁NO₃*ClH Hill Formula: C₄H₁₁NO₃˙ ClH
108219
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Tabela kluczowych gatunków

CAS #EC NumberHill FormulaChemical FormulaMolar Mass
1185-53-1214-684-5C₄H₁₁NO₃˙ ClHC₄H₁₁NO₃*ClH157.60 g/mol

Products

Numer katalogowyOpakowanie Ilość/opak.
1082190003 Pudelko kartonowe 3 x 0,750 kg
1082191000 Butelka plastikowa 1 kg
Description
Catalogue Number108219
SynonymsTrometamol, Aminomethylidine trimethanol, 2-Amino-2-hydroxymethyl-1.3-propanediol, TRIS-buffer
DescriptionTris(hydroxymethyl)aminomethane hydrochloride
References
Product Information
CAS number1185-53-1
EC number214-684-5
Hill FormulaC₄H₁₁NO₃˙ ClH
Chemical formulaC₄H₁₁NO₃*ClH
Molar Mass157.60 g/mol
HS Code2922 19 99
Structure formula ImageStructure formula Image
Quality LevelMQ500
Applications
Biological Information
Physicochemical Information
Density1.28 g/cm3 (20.2 °C)
Melting Point150.7 °C
pH value4.2 (100 g/l, H₂O, 20 °C)
Vapor pressure<0.1 hPa (50 °C)
Solubility561 g/l rozpuszczalny
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Storage class10 - 13 Inne substancje ciekłe i stałe
WGKWGK 1 lekkie zanieczyszczenie wody
Disposal3
Względnie niereaktywne odczynniki organiczne należy zbierać w Kategorii A. Odczynniki chlorowcowane należy umieszczać w Kategorii B. Do pozostałości stałych stosować Kategorię C.
Safety Information
Product Usage Statements
Storage and Shipping Information
StoragePrzechowywać w +15°C do +25°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Appearancewhite to almost white, crystalline powder
Assay (alkalimetric, calculated on dried substance)≥ 99.0 %
Identity (IR-spectrum)conforms
pH-value (0.5 mol/l, water)3.5 - 5.0
Melting point147 - 153 °C
UV-Absorption (230 nm; 10 %; 1 cm; water)≤ 0.1
UV-Absorption (260 nm; 10 %, 1 cm; water)≤ 0.06
UV-Absorption (280 nm; 10 %; 1 cm; water)≤ 0.06
UV-Absorption (300 nm; 10 %; 1 cm; water)≤ 0.02
UV-Absorption (400 nm; 10 %; 1 cm; water)≤ 0.01
Residual solvents (ICHQ3C) of class 2 (Methanol)≤ 3000 ppm
Residual solvents (ICHQ3C) of class 2 (Nitromethane)≤ 50 ppm
Residual solvents (ICHQ3C) of class 3 (Ethanol)≤ 5000 ppm
Residual solvents (ICHQ3C) of class 3 (Ethylmethylketon)≤ 5000 ppm
Other residual solvents (ICH Q3C)excluded by manufacturing process
Sulfated ash≤ 0.03
Loss on Drying (105°C)≤ 0.5
Endotoxins< 2.5
Total aerobic microbial count≤ 10²
Total yeast and mould count
≤ 10²
Salmonella spp.
absent in 10 g
E.coli
absent in 1 g
Staphylococcus aureus
absent in 1 g
Pseudomonas aeruginosa
absent in 1 g
Candida albicans
absent in 1 g
Bile tolerante gram negative bacteria
absent in 1 g
DNases (Exo- and endonucleases)
not detected
Proteases
not detected
RNases
not detected
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Total yeast and mould count
≤ 10²
Salmonella spp.
absent in 10 g
E.coli
absent in 1 g
Staphylococcus aureus
absent in 1 g
Pseudomonas aeruginosa
absent in 1 g
Candida albicans
absent in 1 g
Bile tolerante gram negative bacteria
absent in 1 g
DNases (Exo- and endonucleases)
not detected
Proteases
not detected
RNases
not detected
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Global Trade Item Number
Numer katalogowy GTIN
1082190003 04027269296049
1082191000 04022536101811

Documentation

Emprove Dossier

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6.0

Quality Management Dossier (Open Access)

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Operational Excellence Dossier

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Tris(hydroksymetylo)aminometan, chlorowodorek MSDS

Title

Safety Data Sheet (SDS) 

Tris(hydroksymetylo)aminometan, chlorowodorek Certificates of Analysis

Numer katalogowy OpakowanieSpecyfikacjaNumer partii
1082190003 Pudelko kartonoweDokument ze specyfikacją, w formacie PDF
1082191000 Butelka plastikowaDokument ze specyfikacją, w formacie PDF

Certificates

Title