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567430 Sodium Butyrate - CAS 156-54-7 - Calbiochem

Sodium Butyrate, CAS 156-54-7, is a short chain fatty acid that induces apoptosis in colon carcinoma cells by a p53-independent pathway. Down-regulates the activity of casein kinase II in HT29 cells.

Sodium Butyrate - CAS 156-54-7 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Butyric Acid, Na, NaB, HDAC Inhibitor V

Primary Target: Induce apoptosis
567430
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Przegląd

Replacement Information

Tabela kluczowych gatunków

CAS #Empirical Formula
156-54-7C₄H₇O₂Na

Products

Numer katalogowyOpakowanie Ilość/opak.
567430-250MG Butelka szklana 250 mg
Description
OverviewA short chain fatty acid that has been shown to induce apoptosis in colon carcinoma cell lines by a p53-independent pathway. Inhibits c-myc splicing and interferes with signal transduction processes, including the release of Ca2+ from intracellular stores. Reduces histamine-induced calcium mobilization in C6 glioma cells. Down-regulates the activity of the serine/threonine protein kinase casein kinase II in HT29 cells.
Catalogue Number567430
Brand Family Calbiochem®
SynonymsButyric Acid, Na, NaB, HDAC Inhibitor V
References
ReferencesOu, H.C., et al. 1997. Neuroreport 8, 1375.
Russo, G.L., et al. 1997. Biochem. Biophys. Res. Commun. 233, 673.
Krupitza, G., et al. 1995. Carcinogenesis 16, 1199.
Calabresse, C., et al. 1993. Biochem. Biophys. Res. Commun. 195, 31.
Hague, A., et al. 1993. Int. J. Cancer 55, 498.
Product Information
CAS number156-54-7
ATP CompetitiveN
FormWhite solid
Hill FormulaC₄H₇O₂Na
Chemical formulaC₄H₇O₂Na
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ200
Applications
ApplicationSodium Butyrate, CAS 156-54-7, is a short chain fatty acid that induces apoptosis in colon carcinoma cells by a p53-independent pathway. Down-regulates the activity of casein kinase II in HT29 cells.
Biological Information
Primary TargetInduce apoptosis
Purity≥98% by titration
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSET6400000
Safety Information
R PhraseR: 20/21/22-36/37/38

Harmful by inhalation, in contact with skin and if swallowed.
Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numer katalogowy GTIN
567430-250MG 04055977267273

Documentation

Sodium Butyrate - CAS 156-54-7 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

Sodium Butyrate - CAS 156-54-7 - Calbiochem Certificates of Analysis

TitleLot Number
567430

References

Przegląd literatury
Ou, H.C., et al. 1997. Neuroreport 8, 1375.
Russo, G.L., et al. 1997. Biochem. Biophys. Res. Commun. 233, 673.
Krupitza, G., et al. 1995. Carcinogenesis 16, 1199.
Calabresse, C., et al. 1993. Biochem. Biophys. Res. Commun. 195, 31.
Hague, A., et al. 1993. Int. J. Cancer 55, 498.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision11-September-2008 RFH
SynonymsButyric Acid, Na, NaB, HDAC Inhibitor V
DescriptionA short chain fatty acid that has been shown to induce apoptosis in colon carcinoma cell lines in a p53-independent pathway. Inhibits c-myc splicing and interferes with signal transduction processes, including the release of Ca2+ from intracellular stores. Downregulates the activity of serine/threonine protein kinase casein kinase II in HT29 cells.
FormWhite solid
CAS number156-54-7
RTECSET6400000
Chemical formulaC₄H₇O₂Na
Structure formulaStructure formula
Purity≥98% by titration
SolubilityH₂O (2 mg/ml)
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Irritant
ReferencesOu, H.C., et al. 1997. Neuroreport 8, 1375.
Russo, G.L., et al. 1997. Biochem. Biophys. Res. Commun. 233, 673.
Krupitza, G., et al. 1995. Carcinogenesis 16, 1199.
Calabresse, C., et al. 1993. Biochem. Biophys. Res. Commun. 195, 31.
Hague, A., et al. 1993. Int. J. Cancer 55, 498.