573102 Sigma-AldrichSTAT3 Inhibitor VI, S3I-201 - CAS 501919-59-1 - Calbiochem
STAT3 Inhibitor VI, S3I-201, CAS 501919-59-1, is a cell-permeable compound that binds Stat3-SH2 domain and blocks Stat3 phosphorylation, dimerization, DNA-binding, & Stat3-dependent transcription.
More>> STAT3 Inhibitor VI, S3I-201, CAS 501919-59-1, is a cell-permeable compound that binds Stat3-SH2 domain and blocks Stat3 phosphorylation, dimerization, DNA-binding, & Stat3-dependent transcription. Less<<Synonyms: 2-Hydroxy-4-(((4-methylphenyl)sulfonyloxy)acetyl)amino)-benzoic acid, NSC 74859
Recommended Products
Przegląd
Replacement Information |
---|
Tabela kluczowych gatunków
CAS # | Empirical Formula |
---|---|
501919-59-1 | C₁₆H₁₅NO₇S |
Products
Numer katalogowy | Opakowanie | Ilość/opak. | |
---|---|---|---|
573102-10MG | Ampulka plastikowa | 10 mg |
Description | |
---|---|
Overview | A cell-permeable amidosalicylic acid compound that binds Stat3-SH2 domain and prevents Stat3 phosphorylation/activation, dimerization, DNA-binding, and Stat3-dependent transcription. Shown to arrest Stat3-dependent tumor growth both in cultures in vitro (effective conc. ≤100 µM) and in a murine xenograft model in vivo (5 mg/kg, i.v.). Also available as a 50 mM solution in DMSO (Cat. No. 573130). |
Catalogue Number | 573102 |
Brand Family | Calbiochem® |
Synonyms | 2-Hydroxy-4-(((4-methylphenyl)sulfonyloxy)acetyl)amino)-benzoic acid, NSC 74859 |
References | |
---|---|
References | Lin, L., et al. 2009. Oncogene, 28, 961. Siddiquee, K., et al. 2007. Proc. Natl. Acad. Sci. USA 104, 7391. |
Product Information | |
---|---|
CAS number | 501919-59-1 |
Form | Light beige solid |
Hill Formula | C₁₆H₁₅NO₇S |
Chemical formula | C₁₆H₁₅NO₇S |
Structure formula Image | |
Quality Level | MQ100 |
Applications |
---|
Biological Information | |
---|---|
Purity | ≥95% by HPLC |
Physicochemical Information |
---|
Dimensions |
---|
Materials Information |
---|
Toxicological Information |
---|
Safety Information according to GHS |
---|
Safety Information |
---|
Product Usage Statements |
---|
Packaging Information | |
---|---|
Packaged under inert gas | Packaged under inert gas |
Transport Information |
---|
Supplemental Information |
---|
Specifications |
---|
Global Trade Item Number | |
---|---|
Numer katalogowy | GTIN |
573102-10MG | 04055977266429 |
Documentation
STAT3 Inhibitor VI, S3I-201 - CAS 501919-59-1 - Calbiochem MSDS
Title |
---|
STAT3 Inhibitor VI, S3I-201 - CAS 501919-59-1 - Calbiochem Certificates of Analysis
Title | Lot Number |
---|---|
573102 |
References
Przegląd literatury |
---|
Lin, L., et al. 2009. Oncogene, 28, 961. Siddiquee, K., et al. 2007. Proc. Natl. Acad. Sci. USA 104, 7391. |
Technical Info
Title |
---|
JAK/STAT Signaling Research Focus |