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14-592M PTPMEG-2 Protein, 250 µg

N-terminal GST-tagged, recombinant human PTP-MEG2, amino acid residues 283-end. For use in Phosphatase Assays.

14-592M
250 µg  Also available in 10 μg size (cat#14-592) and in bulk (cat# 14-592-K).
Purchase on Sigma-Aldrich

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Replacement Information
Description
Catalogue Number14-592M
Brand Family Upstate
Trade Name
  • Upstate
DescriptionPTPMEG-2 Protein, 250 µg
OverviewN-terminal GST-tagged, recombinant human PTP-MEG2, amino acid residues 283-end.
References
Product Information
Quality LevelMQ300
Applications
ApplicationN-terminal GST-tagged, recombinant human PTP-MEG2, amino acid residues 283-end. For use in Phosphatase Assays.
Key Applications
  • Phosphatase Assay
Biological Information
SourceExpressed in E. coli
Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme
Entrez Gene Number
Entrez Gene SummaryThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain that shares a significant similarity with yeast SEC14, which is a protein that has phosphatidylinositol transfer activity and is required for protein secretion through the Golgi complex in yeast. This PTP was found to be activated by polyphosphoinositide, and is thought to be involved in signaling events regulating phagocytosis.
Gene Symbol
  • PTPN9
  • PTPase-MEG2
  • MEG2
Protein TargetPTPMEG-2
Purification MethodGlutathione-agarose
Target Sub-FamilyTyr phosphatase
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P43378 # Protein-tyrosine phosphatase that could participate in the transfer of hydrophobic ligands or in functions of the Golgi apparatus.
SIZE: 593 amino acids; 68020 Da
SUBCELLULAR LOCATION: Cytoplasm (Probable).
SIMILARITY: SwissProt: P43378 ## Belongs to the protein-tyrosine phosphatase family. Non-receptor class 3 subfamily. & Contains 1 CRAL-TRIO domain. & Contains 1 tyrosine-protein phosphatase domain.
Molecular Weight62.5kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated by dephosphorylation of 100μM DiFMUP
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions6 months at -70°C
Packaging Information
Material Size250 µg
Material PackageAlso available in 10 μg size (cat#14-592) and in bulk (cat# 14-592-K).
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numer katalogowy GTIN
14-592M 04053252586101

Documentation

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Alternative Packsize

Numer katalogowy Opis
14-592 PTPMEG-2 Protein, 10 µg

Product Families

Kinase & Phosphatase Products

Millipore offers a large portfolio of Kinases, Phophatases, Substrates, Inhibitors, Kits, reagents & tools for Signaling research. See below for a list of these products, in multiple pack sizes.
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Kategorie

Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Phosphatases
Life Science Research > Proteins and Enzymes > Purified Phosphatases