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MAIPN4550 MultiScreen-IP Filter Plate, 0.45 µm, clear, non-sterile

MAIPN4550
50  
Purchase on Sigma-Aldrich

Przegląd

Replacement Information
Description
Catalogue NumberMAIPN4550
Trade Name
  • MultiScreen
DescriptionMultiScreen-IP Filter Plate, 0.45 µm, clear, non-sterile
Background InformationIncreasing drug candidate predictability earlier in the discovery pipeline using non-cell-based assays can improve candidate throughput during the ADME stage. Non-cell-based permeability assays are predictive models for oral absorption of development candidates.

MultiScreen Permeability, MultiScreen-IP, and MultiScreen Acceptor plates support artificial membrane strategies for predicting passive transport.

Membranes have uniform pore structure and density for reliable transport:
- Individual wells minimize candidate cross-talk
- Compatibility with automated liquid handling systems increases throughput

Permeability Assay:
- The MultiScreen Permeability plate has a polycarbonate membrane, which supports a hexane/hexadecane artificial layer for permeability assays.1

PAMPA Assay:
- The MultiScreen-IP plate has a hydrophobic PVDF membrane, which supports a lipid bilayer for PAMPA asays.2,3

MultiScreen Acceptor Plate:
- The MultiScreen Acceptor plate can be used with either plate to capture passively transported compounds. Constructed of 100% PTFE, the plate can improve LC/MS results depending on the charge of the small molecules being evaluated.
References
Product Information
HS Code8421 29 90
Automation CompatibleNo
Filter CodeIP
Color CodeClear
Number of Wells96
Quality LevelMQ400
Applications
ApplicationNon-sterile, clear 96-well filter plate with 0.45 um pore size Hydrophobic PVDF membrane for Avidin-biotin Linkages, DNA-binding Proteins, Protein Binding & PAMPA. Comes in a pack of 50.
Key Applications
  • Avidin-biotin Linkages
  • DNA-binding Proteins
  • Protein Binding
  • PAMPA
Biological Information
MediaImmobilon®-P
SterilityNon-Sterile
Physicochemical Information
Pore Size0.45 µm
Dimensions
Filtration Area0.3cm2
Volume50 µL–250 µL
Materials Information
Chemistry
  • Hydrophobic Polyvinylidene Fluoride (PVDF)
Device Material
  • Acrylic
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Packaging Information
Material Size50
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numer katalogowy GTIN
MAIPN4550 04053252361296

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Life Science Research > Cell Culture and Systems > Cell Culture Flasks, Plates, & Slides > Multiwell Plates