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FCMAB408PE Milli-Mark® Anti-GABA A Receptor β2/3-PE Antibody, clone 62-3G1

Milli-Mark Anti-GABA A Receptor β2/3-PE Antibody, clone 62-3G1 detects level of Milli-Mark GABA A Receptor β2/3-PE & has been published & validated for use in Flow Cytometry.

Milli-Mark® Anti-GABA A Receptor β2/3-PE Antibody, clone 62-3G1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Neurotransmitters & Receptors Gene Symbol: GABRA1, GABA, EJM UniProt Number: P14867
FCMAB408PE
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Tabela kluczowych gatunków

Species ReactivityKey ApplicationsHostFormatAntibody Type
RFCMPhycoerythrinMonoclonal Antibody
Description
Catalogue NumberFCMAB408PE
Trade Name
  • Milli-Mark
DescriptionMilli-Mark® Anti-GABA A Receptor β2/3-PE Antibody, clone 62-3G1
Alternate Names
  • Gamma-amino butyric acid receptor subunit alpha-1
  • GABA(A) receptor subunit alpha-1
  • gamma-aminobutyric acid (GABA) A receptor, alpha 1
Background InformationThe neurotransmitter GABA (gamma-aminobutyric acid) binds to specific transmembrane receptors in the plasma membrane of both pre- and postsynaptic neurons. Three general classes of GABA receptors are known: GABAA and GABAC (ionotropic) receptors and GABAB (metabotropic) receptors. The GABAA (gamma-Aminobutyric Acid type A) receptor is a multiprotein complex that acts as a ligand-gated chloride channel. These receptors are hetero-oligomers, for which 6 subunits are currently known (a, b, g, d, e and r). There are at least 3 different isoforms of the beta subunit, and receptor subunit expression varies during development. Additionally, GABAA receptors are important in regulating the reinforcing properties of alcohol, and expression of the alpha1 and beta 2/3 subunits increase upon chronic exposure to alcohol, and may be potential therapeutic targets for alcohol dependency. The beta 2 subunit is required for receptor assembly and surface expression, while mice with an inactivated beta3 subunit exhibit epilepsy and cleft palate.
References
Product Information
FormatPhycoerythrin
Control
  • B35 cells
PresentationPurified mouse monoclonal IgG1 conjugated to PE in PBS with 0.1% sodium azide and 15 mg/mL BSA.
Quality LevelMQ100
Applications
ApplicationMilli-Mark Anti-GABA A Receptor β2/3-PE Antibody, clone 62-3G1 detects level of Milli-Mark GABA A Receptor β2/3-PE & has been published & validated for use in Flow Cytometry.
Key Applications
  • Flow Cytometry
Biological Information
ImmunogenAffinity-purified GABAA receptor isolated from bovine brain.
Clone62-3G1
HostMouse
IsotypeIgG1
Species Reactivity
  • Rat
Species Reactivity NoteDemonstrated to react with Rat. Predicted to react with Bovine based on immunogen design.
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • GABRA1
  • GABA
  • EJM
Purification MethodProtein G Purified
UniProt Number
Molecular Weight55 and 57 kDa calculated. Specific for the GABAA Receptor β2 subunit, MW ~55 kDa and β3 subunit, MW ~57 kDa.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by flow cytometry using B35 cells
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.
Packaging Information
Material Size100 tests
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numer katalogowy GTIN
FCMAB408PE 04053252820748

Documentation

Milli-Mark® Anti-GABA A Receptor β2/3-PE Antibody, clone 62-3G1 MSDS

Title

Safety Data Sheet (SDS) 

Milli-Mark® Anti-GABA A Receptor β2/3-PE Antibody, clone 62-3G1 Certificates of Analysis

TitleLot Number
Milli-Mark#174; Anti-GABA A Receptor 2/3-PE, clone 62-3G1 - Q2075188 Q2075188
Milli-Mark® Anti-GABA A Receptor β2/3-PE, clone 62-3G1 - 3140434 3140434
Milli-Mark® Anti-GABA A Receptor β2/3-PE, clone 62-3G1 -2527490 2527490
Milli-Mark® Anti-GABA A Receptor β2/3-PE, clone 62-3G1 -2719445 2719445
Milli-Mark® Anti-GABA A Receptor β2/3-PE, clone 62-3G1 Conjugate 2884265