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FCMAB169C5 Milli-Mark Anti-CD3 -PECy5 Antibody, clone UCHT1

This Milli-Mark Anti-CD3 -PECy5 Antibody, clone UCHT1 is validated for use in FC for the detection of CD3.

Milli-Mark Anti-CD3 -PECy5 Antibody, clone UCHT1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology UniProt Number: P20963
FCMAB169C5
100 tests  
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Tabela kluczowych gatunków

Species ReactivityKey ApplicationsHostFormatAntibody Type
HFCMPhycoerythrin/Cy5Monoclonal Antibody
Description
Catalogue NumberFCMAB169C5
Trade Name
  • Milli-Mark
DescriptionMilli-Mark Anti-CD3 -PECy5 Antibody, clone UCHT1
Alternate Names
  • T-cell receptor
Background InformationHuman TCR/CD3 is a complex structure on the lymphocyte surface. It consists of the TCR alpha beta or TCR gamma delta heterodimer and the associated CD3 complex. The CD3 complex is composed of six polypeptides with usually four different transmembrane CD3 chains, gamma, delta, epsilon. and zeta. Three different dimers, gamma epsilon, delta epsilon, and zeta zeta, constitute the CD3 complex. The MW of CD3epsilon is 20 000 (Campana, 1987). CD3 is first detectable in early thymocytes and its appearance probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, during early stages of maturation, the CD3 antigen is predominantly present in the cell cytoplasm. In medullary thymocyles, the CD3 antigen is predominantly detected on the cell surface (Swerdlow, 1988; Beverley, 1981). The majority of T cell neoplasms also expresses CD3, but it is absent from non-T-cell lymphoid malignancies (McMichael, 1987). Consistent with the pattern of synthesis of the antigen in normal thymocytes, the earliest site detectable within neoplastic cells is the cell cytoplasm (Swerdlow, 1988).
Product Information
FormatPhycoerythrin/Cy5
Control
  • Human Lymphocytes
PresentationPurified Mouse monoclonal IgG1 conjugated to PE/Cy5 in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2
Quality LevelMQ100
Applications
ApplicationThis Milli-Mark Anti-CD3 -PECy5 Antibody, clone UCHT1 is validated for use in FC for the detection of CD3.
Key Applications
  • Flow Cytometry
Biological Information
ImmunogenHuman infant thymocytes and lymphocytes from a patient with Sézary disease.
CloneUCHT1
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
SpecificityAntibody recognizes Human CD3 antigen.
IsotypeIgG1κ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Purification MethodProtein A Purfied
UniProt Number
Molecular Weight 20 kDa (Campana, 1987)
Product Usage Statements
Quality AssuranceEvaluated by flow cytometry using Human Lymphocytes.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
Packaging Information
Material Size100 tests
Global Trade Item Number
Numer katalogowy GTIN
FCMAB169C5 04053252746338