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108396 L-Tryptofan

EMPROVE® EXPERT Ph Eur,BP,JP,USP

L-Tryptofan MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Trp

CAS #: 73-22-3 EC Number: 200-795-6 Molar Mass: 204.23 g/mol Hill Formula: C₁₁H₁₂N₂O₂ Grade: Ph Eur,BP,JP,USP
108396
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Tabela kluczowych gatunków

CAS #EC NumberHill FormulaMolar MassGrade Value
73-22-3200-795-6C₁₁H₁₂N₂O₂204.23 g/molPh Eur,BP,JP,USP

Products

Numer katalogowyOpakowanie Ilość/opak.
1083961000 Butelka plastikowa 1 kg
1083969010 Beben plastikowy 10 kg
Description
Catalogue Number108396
SynonymsTrp
References
Product Information
CAS number73-22-3
EC number200-795-6
GradePh Eur,BP,JP,USP
Hill FormulaC₁₁H₁₂N₂O₂
Molar Mass204.23 g/mol
HS Code2933 99 99
Structure formula ImageStructure formula Image
Quality LevelMQ500
Applications
Biological Information
Physicochemical Information
Melting Point290 °C (rozkład)
pH value5.5 - 7 (1 g/l, H₂O, 25 °C)
Bulk density400 kg/m3
Solubility10 g/l
Dimensions
Materials Information
Toxicological Information
LD 50 oralLD50 Szczur 16000 mg/kg
Safety Information according to GHS
RTECSYN6130000
Storage class10 - 13 Inne substancje ciekłe i stałe
WGKWGK 1 lekkie zanieczyszczenie wody
Disposal3
Względnie niereaktywne odczynniki organiczne należy zbierać w Kategorii A. Odczynniki chlorowcowane należy umieszczać w Kategorii B. Do pozostałości stałych stosować Kategorię C.
Safety Information
Product Usage Statements
Storage and Shipping Information
StoragePrzechowywać w +2°C do +30°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Assay (perchloric acid titration, calculated on dried substance)98.5 - 101.0 %
Identity (IR-spectrum)passes test
Identity (specific rotation)passes test
Appearancewhite to almost white, crystalline or amorphous powder
Appearance of solution (10 g/l, Hydrochloric acid 1 mol/l)clear and not more intense in color than reference solution BY₆
Appearance of solution (20 g/l, hydrochloric acid 2 mol/l)clear
pH (10 g/l, CO₂-free water)5.5 - 6.4
Spec. rotation (α 20/D, 10 g/l, water, calc. on dried substance)-30.0 to -33.0
Spec. rotation (α 25/D, 10 g/l, water, calc. on dried substance)-29.4 to -32.8
Spec. rotation (α 20/D, 10 g/l, water, previously dried substance)-30.0 to -33.0
Chloride (Cl)≤ 200 ppm
Sulfate (SO₄)≤ 200 ppm
Heavy metals (as Pb)≤ 20 ppm
Fe (Iron)≤ 20 ppm
As (Arsenic)≤ 2 ppm
Ninhydrin-positive substances (LC) (any ninhydrin-positive impurity)≤ 0.2 %
Ninhydrin-positive substances (LC) (ammonium (570 nm))≤ 0.02 %
Ninhydrin-positive substances (LC) (total impurities)≤ 0.5 %
Related substances (HPLC)passes test
Impurity A ((1,1‘-ethylidenebistryptophan) Peak-E) (acc. to Ph Eur)≤ 10 ppm
Sum of impurities with RT < tryptophan-peak (acc. to Ph Eur)≤ 100 ppm
Sum of impurities with RT > tryptophan-peak and up to1,8 times the RT ofacetyltryptophan (acc. to Ph Eur)≤ 300 ppm
Impurity A ((1,1‘-ethylidenebistryptophan) Peak-E) (acc. to USP)≤ 10 ppm
Sum of impurities with RT < tryptophan-peak (acc. to USP)≤ 100 ppm
Sum of impurities with RT > tryptophan-peak, without tryptophan-peak andpeak of „Related Compound B“ (N-acetyltryptophan) (acc. to USP)≤ 300 ppm
Related substances (TLC)passes test
Residual solvents (ICH (Q3C))excluded by manufacturing process
Sulfated ash (600 °C)≤ 0.1 %
Loss on drying (105 °C; 3 h)≤ 0.30 %
Bacterial endotoxins≤ 10 I.U./g
Microbiological test (total aerobic microbial count (TAMC))≤ 100 CFU/g
Microbiological test (total yeast and mould count (TYMC))≤ 100 CFU/g
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph. Eur., BP, JP, USP.
Global Trade Item Number
Numer katalogowy GTIN
1083961000 04022536104003
1083969010 04022536732701

Documentation

Emprove Dossier

TitleVersion
9.0

Quality Management Dossier (Open Access)

Title

Operational Excellence Dossier

Title

L-Tryptofan MSDS

Title

Safety Data Sheet (SDS) 

L-Tryptofan Certificates of Analysis

Numer katalogowy OpakowanieSpecyfikacjaNumer partii
1083961000 Butelka plastikowaDokument ze specyfikacją, w formacie PDF
1083969010 Beben plastikowyDokument ze specyfikacją, w formacie PDF

Certificates

Title