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324801 InSolution™ Epoxomicin, Synthetic - Calbiochem

InSolution™ Epoxomicin, Synthetic, is a 1 mM solution of Epoxomicin, Synthetic (Cat. No. 324800) in DMSO.

InSolution™ Epoxomicin, Synthetic - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Proteasome Inhibitor XIV

Primary Target: CT-L,T-L,PGPH activity of proteasome
324801
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Przegląd

Replacement Information

Tabela kluczowych gatunków

Empirical Formula
C₂₈H₅₀N₄O₇

Products

Numer katalogowyOpakowanie Ilość/opak.
324801-50UG Ampulka plastikowa 50 μg
Description
Catalogue Number324801
Brand Family Calbiochem®
SynonymsProteasome Inhibitor XIV
References
ReferencesMeng, L., et al. 1999. Proc. Natl. Acad. Sci. USA 96, 10403.
Sin, N., et al. 1999. Bioorg. Med. Chem. Lett. 9, 2283.
Hanada, M., et al. 1992. J. Antibiot. 45, 1746.
Product Information
ATP CompetitiveN
FormLiquid
FormulationA 1 mM (50 µg/90 µl) solution of Epoxomicin, Synthetic (Cat. No. 324800) in DMSO.
Hill FormulaC₂₈H₅₀N₄O₇
Chemical formulaC₂₈H₅₀N₄O₇
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetCT-L,T-L,PGPH activity of proteasome
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped with Blue Ice or with Dry Ice
Toxicity Irritant
Storage -20°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numer katalogowy GTIN
324801-50UG 04055977216165

Documentation

InSolution™ Epoxomicin, Synthetic - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

InSolution™ Epoxomicin, Synthetic - Calbiochem Certificates of Analysis

TitleLot Number
324801

References

Przegląd literatury
Meng, L., et al. 1999. Proc. Natl. Acad. Sci. USA 96, 10403.
Sin, N., et al. 1999. Bioorg. Med. Chem. Lett. 9, 2283.
Hanada, M., et al. 1992. J. Antibiot. 45, 1746.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision20-June-2008 RFH
SynonymsProteasome Inhibitor XIV
DescriptionAn antitumor agent of microbial origin that acts as a potent, highly specific, and irreversible inhibitor of chymotrypsin-like (CT-L), trypsin-like (T-L), and peptidylglutamyl peptide hydrolyzing (PGPH) activities of the proteasome. Modifies the proteasomal catalytic subunits LMP-7, MECL1, and Z. Epoxomicin also displays potent anti-inflammatory activity in vivo.
FormLiquid
FormulationA 1 mM (50 µg/90 µl) solution of Epoxomicin, Synthetic (Cat. No. 324800) in DMSO.
Intert gas (Yes/No) Packaged under inert gas
Chemical formulaC₂₈H₅₀N₄O₇
Structure formulaStructure formula
Purity≥95% by HPLC
Storage Protect from light
-20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Toxicity Irritant
ReferencesMeng, L., et al. 1999. Proc. Natl. Acad. Sci. USA 96, 10403.
Sin, N., et al. 1999. Bioorg. Med. Chem. Lett. 9, 2283.
Hanada, M., et al. 1992. J. Antibiot. 45, 1746.