370677 Sigma-AldrichGuanosine 3ʹ,5ʹ-cyclic Monophosphorothioate, 8-(4-Chlorophenylthio)-, Rp-Isomer, Triethylammonium Salt - Calbiochem
A potent, cell-permeable, and metabolically-stable inhibitor of protein kinase G Iα, Iβ, and type II.
More>> A potent, cell-permeable, and metabolically-stable inhibitor of protein kinase G Iα, Iβ, and type II. Less<<Synonyms: Rp-8-pCPT-cGMPS, TEA, PKG Inhibitor III
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Przegląd
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Tabela kluczowych gatunków
Empirical Formula |
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C₁₆H₁₅ClN₅O₆PS₂ · C₆H₁₅N |
Products
Numer katalogowy | Opakowanie | Ilość/opak. | |
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370677-1UMOL | Ampulka plastikowa | 1 umol |
Description | |
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Overview | A potent, cell-permeable, and metabolically-stable inhibitor of protein kinase G Iα, Iβ, and type II. Significantly more lipophilic and membrane-permeable than Rp-cGMPS or Rp-8-Br-cGMPS (Cat. No. 370674). Note: 1 µmol = 0.61 mg. |
Catalogue Number | 370677 |
Brand Family | Calbiochem® |
Synonyms | Rp-8-pCPT-cGMPS, TEA, PKG Inhibitor III |
Product Information | |
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ATP Competitive | N |
Declaration | Sold under license of U.S. Patent 5,625,056, Patents DE 3,802,865.4, and DE 4,217,679 issued to BIOLOG LSI. |
Form | Lyophilized |
Hill Formula | C₁₆H₁₅ClN₅O₆PS₂ · C₆H₁₅N |
Chemical formula | C₁₆H₁₅ClN₅O₆PS₂ · C₆H₁₅N |
Hygroscopic | Hygroscopic |
Reversible | N |
Structure formula Image | |
Quality Level | MQ100 |
Applications |
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Biological Information | |
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Primary Target | PKG1α |
Purity | ≥99% by HPLC |
Physicochemical Information | |
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Cell permeable | Y |
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Safety Information according to GHS |
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Supplemental Information |
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Specifications |
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Global Trade Item Number | |
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Numer katalogowy | GTIN |
370677-1UMOL | 04055977191707 |
Documentation
Guanosine 3ʹ,5ʹ-cyclic Monophosphorothioate, 8-(4-Chlorophenylthio)-, Rp-Isomer, Triethylammonium Salt - Calbiochem MSDS
Title |
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Guanosine 3ʹ,5ʹ-cyclic Monophosphorothioate, 8-(4-Chlorophenylthio)-, Rp-Isomer, Triethylammonium Salt - Calbiochem Certificates of Analysis
Title | Lot Number |
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370677 |
References
Przegląd literatury |
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Abd Alla, S., et al. 1996. Eur. J. Biochem. 241, 498. Lee, S.J., et al. 1996. Dev. Biol. 180, 324. Van Uffelen, B.E., et al. 1996. J. Leukoc. Biol. 60, 94. Willmott, N., et al. 1996. J. Biol. Chem. 271, 3699. Butt, E., et al. 1994. Eur. J. Pharmacol. 269, 265. |