Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

GF304 GM-CSF Protein, Human Recombinant Animal Free

GF304
20 µg  
Purchase on Sigma-Aldrich

Przegląd

Tabela kluczowych gatunków

SourcePurity
E. coli Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
Description
Catalogue NumberGF304
DescriptionGM-CSF Protein, Human Recombinant Animal Free
Alternate Names
  • GMCSF
  • M-CSF
  • CSF-1
  • Granulocyte Colony Stimulating Factor
  • Macrophage Colony Stimulating Factor
  • Granulocyte/Macrophage Colony Stimulating Factor
  • G-CSF
Background InformationGranulocyte/Macrophage Colony-Stimulating Factor (GM-CSF) was initially characterized as a factor that can support the in vitro colony formation of granulocyte macrophage progenitors. It is also a growth factor for erythroid, megakaryocyte, and eosinophil progenitors. GMCSF is produced by a number of different cell types (including T cells, B cells, macrophages, mast cells, endothelial cells, fibroblasts, and adipocytes) in response to cytokine or inflammatory stimuli. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant human GM-CSF is a 14.6 kDa globular protein consisting of 128 amino acids containing two intramolecular disulfide bonds and two potential N-linked glycosylation sites.
Product Information
Formulation
PresentationProduct is filtered through a 0.2 micron filter before lyophilization.
Quality LevelMQ100
Applications
ApplicationThe GM-CSF protein was initially characterized as a factor that can support the in vitro colony formation of granulocyte macrophage progenitors. The Recombinant animal free human GM-CSF is manufactured using all non-animal reagents.
Biological Information
PurityProduct is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
SourceE. coli
Cross ReactivityNone
Entrez Gene Number
UniProt Number
Product Usage Statements
Quality AssuranceBioactivity assay: The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore at -20°C for up to 6 months from date of receipt.
Packaging Information
Material Size20 µg
Global Trade Item Number
Numer katalogowy GTIN
GF304 04053252691454