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239900 Cypermethrin - CAS 52315-07-8 - Calbiochem

Synthetic type II pyrethroid. Potent inhibitor of calcineurin (protein phosphatase 2B; IC₅₀ = 40 pM). May also have varied effects on ion channels.

Cypermethrin - CAS 52315-07-8 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (R,S)-α-Cyano-3-phenoxybenzyl-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate

Primary Target: calcineurin
239900
Purchase on Sigma-Aldrich

Przegląd

Replacement Information

Tabela kluczowych gatunków

CAS #Empirical Formula
52315-07-8C₂₂H₁₉Cl₂NO₃

Products

Numer katalogowyOpakowanie Ilość/opak.
239900-10MG Beben aluminiowy 10 mg
Description
OverviewSynthetic type II pyrethroid. Potent inhibitor of calcineurin (protein phosphatase 2B; IC50 = 40 pM). May also have varied effects on ion channels.
Catalogue Number239900
Brand Family Calbiochem®
Synonyms(R,S)-α-Cyano-3-phenoxybenzyl-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate
References
ReferencesRichter, A., et al. 1995. Biochem. Pharmacol. 49, 367.
Wang, J.H., and Stelzer, A. 1994. NeuroReport 5, 2377.
Enan, E., and Matsumura, F. 1992. Biochem. Pharmacol. 43, 1777.
Narahasi, T. 1992. Trends Pharmacol. Sci. 13, 236.
Product Information
CAS number52315-07-8
ATP CompetitiveN
FormOil
Hill FormulaC₂₂H₁₉Cl₂NO₃
Chemical formulaC₂₂H₁₉Cl₂NO₃
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Targetcalcineurin
Primary Target IC<sub>50</sub>40 pM against calcineurin (protein phosphatase 2B
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSGZ1250000
Safety Information
R PhraseR: 25-36/38

Toxic if swallowed.
Irritating to eyes and skin.
S PhraseS: 26-36/37/39-45

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Toxic
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage +2°C to +8°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numer katalogowy GTIN
239900-10MG 04055977199055

Documentation

Cypermethrin - CAS 52315-07-8 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

Cypermethrin - CAS 52315-07-8 - Calbiochem Certificates of Analysis

TitleLot Number
239900

References

Przegląd literatury
Richter, A., et al. 1995. Biochem. Pharmacol. 49, 367.
Wang, J.H., and Stelzer, A. 1994. NeuroReport 5, 2377.
Enan, E., and Matsumura, F. 1992. Biochem. Pharmacol. 43, 1777.
Narahasi, T. 1992. Trends Pharmacol. Sci. 13, 236.

Brochure

Title
Protein Phosphatases Technical Bulletin

Citations

Tytuł
  • Mike T. Lin, et al. (2005) Ca2+-activated K+ channel-associated phosphatase and kinase activities during development. American Journal of Physiology Heart and Circulatory Physiology 289, H414-H425.
    		•
    Data Sheet

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision29-February-2008 JSW
    Synonyms(R,S)-α-Cyano-3-phenoxybenzyl-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate
    DescriptionType II pyrethroid insecticide. Potent inhibitor of calcineurin (protein phosphatase 2B, IC50 = 40 pM). May also have varied effects on ion channels.
    FormOil
    CAS number52315-07-8
    RTECSGZ1250000
    Chemical formulaC₂₂H₁₉Cl₂NO₃
    Structure formulaStructure formula
    Purity≥95% by HPLC
    SolubilityDMSO (15 mg/ml) or Ethanol (5 mg/ml)
    Storage +2°C to +8°C
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    Toxicity Toxic
    Merck USA index14, 2767
    ReferencesRichter, A., et al. 1995. Biochem. Pharmacol. 49, 367.
    Wang, J.H., and Stelzer, A. 1994. NeuroReport 5, 2377.
    Enan, E., and Matsumura, F. 1992. Biochem. Pharmacol. 43, 1777.
    Narahasi, T. 1992. Trends Pharmacol. Sci. 13, 236.
    Citation
  • Mike T. Lin, et al. (2005) Ca2+-activated K+ channel-associated phosphatase and kinase activities during development. American Journal of Physiology Heart and Circulatory Physiology 289, H414-H425.
    		•