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MABN139 Anti-mGluR5 Antibody, clone 11D9.1

Detect mGluR5 using this mouse monoclonal antibody, Anti-mGluR5 Antibody, clone 11D9.1 validated for use in western blotting & IHC.

Anti-mGluR5 Antibody, clone 11D9.1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Signaling Gene Symbol: GRM5, GPRC1E, MGLUR5 UniProt Number: P41594
MABN139
100 µg  
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Tabela kluczowych gatunków

Species ReactivityKey ApplicationsHostFormatAntibody Type
R, HWB, IHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABN139
DescriptionAnti-mGluR5 Antibody, clone 11D9.1
Alternate Names
  • Metabotropic glutamate receptor 5
  • mGluR5
Background InformationMetabotropic glutamate receptor 5 (mGluR5) is a member of the G-protein coupled receptor family and functions as a receptor for glutamate. mGluR5 activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current.
References
Product Information
FormatPurified
HS Code3002 15 90
Control
  • Rat brain micropreparation tissue lysate
PresentationPurified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect mGluR5 using this mouse monoclonal antibody, Anti-mGluR5 Antibody, clone 11D9.1 validated for use in western blotting & IHC.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected mGluR5 in normal human brain tissue.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to human mGluR5.
Clone11D9.1
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
IsotypeIgG2bκ
Species Reactivity
  • Rat
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • GRM5
  • GPRC1E
  • MGLUR5
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~150 kDa observed. The calculated molecular weight is 130 kDa, however mGluR5 has been shown as a ~150 kDa band in western blots (Romano, C., et al. (1996). J Biol Chem. 271(45):28612-28616).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in rat brain micropreparation tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected mGluR5 in 10 µg of rat brain micropreparation tissue lysate. The lysate was not boiled during preperation for western blotting.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numer katalogowy GTIN
MABN139 04053252880216

Documentation

Anti-mGluR5 Antibody, clone 11D9.1 MSDS

Title

Safety Data Sheet (SDS) 

Anti-mGluR5 Antibody, clone 11D9.1 Certificates of Analysis

TitleLot Number
Anti-mGluR5, clone 11D9.1 - 3236370 3236370
Anti-mGluR5, clone 11D9.1 - 3525955 3525955
Anti-mGluR5, clone 11D9.1 - 3899586 3899586
Anti-mGluR5, clone 11D9.1 - 4176596 4176596
Anti-mGluR5, clone 11D9.1 - Q2159801 Q2159801
Anti-mGluR5, clone 11D9.1 -2548724 2548724
Anti-mGluR5, clone 11D9.1 -2566788 2566788
Anti-mGluR5, clone 11D9.1 -2887465 2887465
Anti-mGluR5, clone 11D9.1 Monoclonal Antibody 2976875
Anti-mGluR5, clone 11D9.1 Monoclonal Antibody 2903066

Brochure

Title
Pathways and Biomarkers of Glutamatergic Synapse Flyer