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MABN1594 Anti-WWOX Antibody, clone 12G5

Anti-WWOX Antibody, clone 12G5 | MABN1594 is an antibody against WWOX Antibody for use in Western Blotting, Immunohistochemistry.

Anti-WWOX Antibody, clone 12G5 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Signaling Gene Symbol: Wwox, Wox1
UniProt Number: Q91WL8
MABN1594
100 µg  
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Tabela kluczowych gatunków

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, MWB, IHCRPurifiedMonoclonal Antibody
Description
Catalogue NumberMABN1594
DescriptionAnti-WWOX Antibody, clone 12G5
Alternate Names
  • WW domain-containing oxidoreductase
Background InformationWW domain-containing oxidoreductase (WWOX) is also called Fragile site FRA16D oxidoreductase (FOR). WWOX is a putative oxidoreductase that functions as a tumor suppressor and is involved in apoptosis. WWOX is also required for normal bone development, and inhibits Wnt signaling. WWOX is widely expressed, but is most strongly expressed in testis, prostate, and ovary as well as in cancer cell lines. Certain isoforms (Isoform 5 and isoform 6) are thought to only be expressed in tumor cell lines. WWOX is linked to several cancer types like Esophageal cancer (ESCR).
References
Product Information
FormatPurified
PresentationPurified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-WWOX Antibody, clone 12G5 | MABN1594 is an antibody against WWOX Antibody for use in Western Blotting, Immunohistochemistry.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesWestern Blotting Analysis: 1.0 µg/mL from a representative lot detected WWOX in 10 µg of mouse 11 day embreyo and mouse E13-14 Brain tissue lysate.
Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected WWOX in human cerebellum and human cerebral cortex tissue.
Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected WWOX in mouse cerebellum and mouse hindbrain tissue.
Biological Information
ImmunogenRecombinant protein corresponding to mouse WWOX.
Clone12G5
ConcentrationPlease refer to lot specific datasheet.
HostRat
IsotypeIgG2aκ
Species Reactivity
  • Human
  • Mouse
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • Wwox
  • Wox1
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~46 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in HepG2 cell lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected WWOX in 10 µg of HepG2 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numer katalogowy GTIN
MABN1594 04055977125368