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ABN1010 Anti-Syntaxin 2 Antibody

ABN1010
100 µL  
Purchase on Sigma-Aldrich

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Replacement Information

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Tabela kluczowych gatunków

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABN1010
ReplacesAB5596-50UL
DescriptionAnti-Syntaxin 2 Antibody
Alternate Names
  • Syntaxin-2
  • Syntaxin 2
  • Epimorphin
Background InformationSyntaxin 2 (also known as Epimorphin) is a type one single-transmembrane protein encoded by the STX2 (or EPIM) gene in human. Syntaxin 2 belongs to the syntaxin/epimorphin family of proteins mediating the targeting and fusion of intracellular transport vesicles. Several proteins are involved in membrane fusion events, including the N-ethylmaleimide (NEM)-sensitive factor (NSF), soluble NSF attachment proteins (SNAPs) and SNAP receptors (SNAREs). Syntaxin 2 is found in the plasma membrane and in intracellular vesicular structures where it functions as a target SNARE (t-SNARE). Syntaxin-2 mediates membrane fusion by pairing with a vesicle SNARE (v-SNARE) to form a "trans complex", thereby pulling the taregt and vesicle membranes together. (PMID 15943887).
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ300
Applications
ApplicationAnti-Syntaxin 2 Antibody is an antibody against Syntaxin 2 for use in Western Blotting.
Key Applications
  • Western Blotting
Biological Information
ImmunogenHis-tagged recombinant protein corresponding to human Syntaxin 2.
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • STX2
  • EPIM
  • STX2A
  • STX2B
  • STX2C
Purification MethodAffinity
UniProt Number
Molecular Weight~34 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in human testis tissue lysate.

Western Blotting Analysis: A 1:500 of this antibody detected Syntaxin 2 in 10 µg of human testis tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numer katalogowy GTIN
ABN1010 04055977161885