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MABN629 Anti-PPID Antibody, clone 6A5.1

This Anti-PPID Antibody, clone 6A5.1 is validated for use in Western Blotting and Immunohistochemistry (Paraffin) for the detection of PPID.

Anti-PPID Antibody, clone 6A5.1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Signaling Gene Symbol: PPID, CYP40, CYPD UniProt Number: Q08752
MABN629
100 µg  
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Tabela kluczowych gatunków

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, RWB, IH(P)MPurifiedMonoclonal Antibody
Description
Catalogue NumberMABN629
DescriptionAnti-PPID Antibody, clone 6A5.1
Alternate Names
  • Peptidyl-prolyl cis-trans isomerase D
  • PPIase D
  • 40 kDa peptidyl-prolyl cis-trans isomerase
  • Cyclophilin-40
  • CYP-40
  • Cyclophilin-related protein
  • Rotamase D
Background InformationPPIase D is one of a family peptidyl-prolyl-isomerases that help proteins fold during synthesis. Specifically, PPIases D catalyzes the cis-trans isomerization of proline imidic peptide bonds in peptides. Among the proteins assisted by PPIase D are HSP90, Estrogen receptor, cellular dynein, MYB, ILF2, XRCC6, GNB2L1 and RPS3. PPIase D also may regulate the interactions of other proteins including MYB and AHR. Through its protein folding exercise PPIase D becomes vital for proper protein transport and expression as well. Finally PPIase D is associated with assisting in the response to UV light induced apoptosis, cell viability in anaplastic lymphoma and hepatitis C virus replication and release. PPIase can be found localized in both the cytoplasm and the nucleus and is widely expressed. Note PPIase should not be confused with PPIF, or mitochondrial peptidyl-prolyl cis-trans isomerase F.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-PPID Antibody, clone 6A5.1 is validated for use in Western Blotting and Immunohistochemistry (Paraffin) for the detection of PPID.
Key Applications
  • Western Blotting
  • Immunohistochemistry (Paraffin)
Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected PPID in rat cerebellum tissue.
Biological Information
ImmunogenRecombinant protein corresponding to human PPID.
Clone6A5.1
ConcentrationPlease refer to lot specific datasheet.
HostMouse
IsotypeIgG1κ
Species Reactivity
  • Human
  • Rat
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • PPID
  • CYP40
  • CYPD
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~ 42 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in HepG2 cell lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected PPID in 10 µg of HepG2 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numer katalogowy GTIN
MABN629 04053252986543