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MABE570 Anti-N-CoR1, clone 7A7A9 Antibody

MABE570
100 µL  
Purchase on Sigma-Aldrich

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Species ReactivityKey ApplicationsHostFormatAntibody Type
HIHCMAscitesMonoclonal Antibody
Description
Catalogue NumberMABE570
DescriptionAnti-N-CoR1, clone 7A7A9 Antibody
Alternate Names
  • Nuclear receptor corepressor 1
  • N-CoR
  • N-CoR1
Background InformationNuclear receptor corepressor 1 (N-CoR or N-CoR1), and encoded by the gene name NCOR, mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. N-CoR1 is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. N-CoR1 is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17.
References
Product Information
FormatAscites
PresentationMouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-N-CoR1, clone 7A7A9 Antibody detects level of N-CoR1 & has been published & validated for use in N-CoR1.
Key Applications
  • Immunohistochemistry
Biological Information
ImmunogenPurified recombinant fragment of human N-CoR1 expressed in E. Coli
Clone7A7A9
HostMouse
IsotypeIgG1
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Gene Symbol
  • NCOR1
  • KIAA1047
Purification MethodUnpurified
UniProt Number
Molecular Weight270 kDa calculated
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceImmunohistochemistry Analysis: A 1:200-1,000 dilution from a representative lot detected N-CoR1 in human cerebra and breast carcinoma tissues.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numer katalogowy GTIN
MABE570 04053252957291