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MABD146 Anti-Lefty Antibody, clone 1G9.1

MABD146
100 µg  
Purchase on Sigma-Aldrich

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Species ReactivityKey ApplicationsHostFormatAntibody Type
R, MWBMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABD146
ReplacesMABD186
DescriptionAnti-Lefty Antibody, clone 1G9.1
Alternate Names
  • Left-right determination factor 1
  • Left-right determination factor B
  • Protein lefty-1
  • Protein lefty-B
Background InformationLeft-right determination factor 1 (LEFTY1) also known as Left-right determination factor B, Protein lefty-1, Protein lefty-B, and encoded by the gene name LEFTYB, LEFTY1, LEFTB, is a member of the the TGF-beta family. LEFTY1 collaborates with other members of the TGFβ (Transforming Growth Factor) family to establish a left-right axis that dictates the asymmetrical distribution of internal organs during vertebrate embryogenesis. Mice deficient in LEFTY1 are affected by pulmonary isomerism and abnormal placement of vascular tracts, possibly the result of unregulated expression of LEFTY2 and NODAL.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-Lefty Antibody, clone 1G9.1 | MABD146 is an antibody against Lefty Antibody for use in Western Blotting.
Key Applications
  • Western Blotting
Application NotesWestern Blotting Analysis: 0.5 µg/mL from a representative lot detected Lefty in 10 µg of C2C12 and NIH-3T3 cell lysate.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human Lefty and spans the pro and mature cleavage sites.
Clone1G9.1
ConcentrationPlease refer to lot specific datasheet.
HostMouse
IsotypeIgMκ
Species Reactivity
  • Rat
  • Mouse
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • LEFTY1
  • LEFTB
  • LEFTYB
  • UNQ278/PRO317
Purification MethodPurified by Ion-Exchange Chromatography
UniProt Number
Molecular Weight~40 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in L6 cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected Lefty in 10 µg of L6 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numer katalogowy GTIN
MABD146 04055977123852