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438190 Anti-LRP, Heavy Chain Mouse mAb (8G1)

This Anti-LRP, Heavy Chain Mouse mAb (8G1) is validated for use in ELISA, FC, Immunoblotting, IP, Paraffin Sections, Neutralization Studies for the detection of LRP, Heavy Chain.

Anti-LRP, Heavy Chain Mouse mAb (8G1) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-Low Density Lipoprotein Receptor-Related Protein

438190
Purchase on Sigma-Aldrich

Przegląd

Replacement Information

Tabela kluczowych gatunków

Species ReactivityHostAntibody Type
HMMonoclonal Antibody

Products

Numer katalogowyOpakowanie Ilość/opak.
438190-100UG Butelka szklana 100 μg
Description
OverviewRecognizes the ~515 kDa LRP heavy chain protein.
Catalogue Number438190
Brand Family Calbiochem®
SynonymsAnti-Low Density Lipoprotein Receptor-Related Protein
References
ReferencesMikhailenko, I., et al. 2001. J. Biol. Chem. 276, 39484.
Rebeck, W.G., et al. 2001. Mol. Brain Res. 87, 238.
Strickland, D.K., et al. 1990. J. Biol. Chem. 265, 17401.
Product Information
FormLiquid
FormulationIn 100 mM NaCl, 50 mM phosphate buffer, pH 7.4.
PreservativeNone
Quality LevelMQ100
Applications
Key Applications Enzyme-Linked Immunosorbent Assay
Flow Cytometry
Immunoblotting (Western Blotting)
Immunoprecipitation
Neutralization Studies
Paraffin Sections
Application NotesELISA (see comments)
Flow Cytometry (see comments)
Immunoblotting (1-5 µg/ml)
Immunoprecipitation (see comments)
Paraffin Sections (1-10 µg/ml)
Neutralization Studies (see comments)
Application CommentsRecognizes the low density heavy chain (~515 kDa) by immunoblotting under non-reducing conditions. This antibody has also been reported to work for immunoprecipitation, flow cytometry, and ELISA. Variables associated with assay conditions will dictate the proper working dilution.
Biological Information
Immunogennative LRP from human placenta
ImmunogenHuman
Clone8G1
HostMouse
IsotypeIgG₁
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage -20°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numer katalogowy GTIN
438190-100UG 04055977187007

Documentation

Anti-LRP, Heavy Chain Mouse mAb (8G1) MSDS

Title

Safety Data Sheet (SDS) 

Anti-LRP, Heavy Chain Mouse mAb (8G1) Certificates of Analysis

TitleLot Number
438190

References

Przegląd literatury
Mikhailenko, I., et al. 2001. J. Biol. Chem. 276, 39484.
Rebeck, W.G., et al. 2001. Mol. Brain Res. 87, 238.
Strickland, D.K., et al. 1990. J. Biol. Chem. 265, 17401.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision07-August-2007 RFH
SynonymsAnti-Low Density Lipoprotein Receptor-Related Protein
ApplicationELISA (see comments)
Flow Cytometry (see comments)
Immunoblotting (1-5 µg/ml)
Immunoprecipitation (see comments)
Paraffin Sections (1-10 µg/ml)
Neutralization Studies (see comments)
DescriptionPurified mouse monoclonal antibody. Recognizes the ~515 kDa LRP heavy chain protein.
BackgroundInhibits the binding of LRP (Low Density Lipoprotein Receptor-Related Protein) to α2-macroglobulin. LRP contributes to the pathology of Alzheimer's disease by influencing both the production and clearance of the β-amyloid peptide.
HostMouse
Immunogen speciesHuman
Immunogennative LRP from human placenta
Clone8G1
IsotypeIgG₁
Specieshuman
FormLiquid
FormulationIn 100 mM NaCl, 50 mM phosphate buffer, pH 7.4.
Concentration Label Please refer to vial label for lot-specific concentration
PreservativeNone
CommentsRecognizes the low density heavy chain (~515 kDa) by immunoblotting under non-reducing conditions. This antibody has also been reported to work for immunoprecipitation, flow cytometry, and ELISA. Variables associated with assay conditions will dictate the proper working dilution.
Storage Avoid freeze/thaw
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Toxicity Standard Handling
ReferencesMikhailenko, I., et al. 2001. J. Biol. Chem. 276, 39484.
Rebeck, W.G., et al. 2001. Mol. Brain Res. 87, 238.
Strickland, D.K., et al. 1990. J. Biol. Chem. 265, 17401.