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05-1108 Anti-Insulin Antibody, clone1

Anti-Insulin Antibody, clone1 is an antibody against Insulin for use in IH(P).

Anti-Insulin Antibody, clone1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Insulin/Energy Signaling Gene Symbol: ILPR, IRDN, OTTHUMP00000011161 , OTTHUMP00000011162, OTTHUMP00000196038, insulin, proinsulin UniProt Number: P01308
05-1108
1 mg  
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Tabela kluczowych gatunków

Species ReactivityKey ApplicationsHostFormatAntibody Type
HIH(P)MAffinity PurifiedMonoclonal Antibody
Description
Catalogue Number05-1108
ReplacesCBL71
DescriptionAnti-Insulin Antibody, clone1
Background InformationInsulin is a polypeptide hormone that regulates carbohydrate metabolism. Apart from being the primary agent in carbohydrate homeostasis, it has effects on fat metabolism.
References
Product Information
FormatAffinity Purified
Control
  • Human pancreas tissue.
PresentationThe monoclonal is presented as 1mg in 1ml phosphate buffered saline containing 10mM sodium azide. We recommend that each laboratory determine an optimum working titre for use in its particular application.
Quality LevelMQ100
Applications
ApplicationAnti-Insulin Antibody, clone1 is an antibody against Insulin for use in IH(P).
Key Applications
  • Immunohistochemistry (Paraffin)
Biological Information
ImmunogenBiosynthetic human insulin
CloneMAB1
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
SpecificityThis antibody recognizes an epitope including the amino acid B30.
IsotypeIgG1
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • ILPR
  • IRDN
  • OTTHUMP00000011161
  • OTTHUMP00000011162
  • OTTHUMP00000196038
  • insulin
  • proinsulin
Purification MethodAffinity Purfied
UniProt Number
UniProt SummaryFUNCTION: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
SUBUNIT STRUCTURE: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
SUBCELLULAR LOCATION: Secreted.
INVOLVEMENT IN DISEASE: Defects in INS are the cause of familial hyperproinsulinemia [MIM:176730].
PHARMACEUTICAL USE: Available under the names Humulin or Humalog (Eli Lilly) and Novolin (Novo Nordisk). Used in the treatment of diabetes. Humalog is an insulin analog with 52-Lys-Pro-53 instead of 52-Pro-Lys-53.
SEQUENCE SIMILARITIES: Belongs to the insulin family.
SEQUENCE CAUTION: The sequence AAA59179.1 differs from that shown. Reason: Erroneous gene model prediction.
Molecular WeightApprox. 12 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Immunohistochemistry in human pancreas tissue.
Immunohistochemistry Analysis: 1.25 µg/mL of this antibody detected insulin in human pancreas tissue.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore at 2-8°C and use within 1 year from date of receipt.
Packaging Information
Material Size1 mg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numer katalogowy GTIN
05-1108 04053252365010

Documentation

Anti-Insulin Antibody, clone1 MSDS

Title

Safety Data Sheet (SDS) 

Anti-Insulin Antibody, clone1 Certificates of Analysis

TitleLot Number
Anti-Insulin, clone MAB1 - 2329817 2329817
Anti-Insulin, clone MAB1 - 2375637 2375637
Anti-Insulin, clone MAB1 - 2087825 2087825
Anti-Insulin, clone MAB1 - 2536521 2536521
Anti-Insulin, clone MAB1 - 2906292 2906292
Anti-Insulin, clone MAB1 - 3207641 3207641
Anti-Insulin, clone MAB1 - 3385823 3385823
Anti-Insulin, clone MAB1 - 3539808 3539808
Anti-Insulin, clone MAB1 - 3540415 3540415
Anti-Insulin, clone MAB1 - 3704246 3704246
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