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CBL85 Anti-Endothelin-1 Antibody, clone IC4

Detect Endothelin-1 using this Anti-Endothelin-1 Antibody, clone IC4 validated for use in IHC.

Anti-Endothelin-1 Antibody, clone IC4 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: CNS Control of Metabolism, Hormones & Receptors Gene Symbol: EDN1, OTTHUMP00000039245, Preproendothelin-1, ET1, PPET1, ET-1, HDLCQ7 UniProt Number: P05305
CBL85
1 mg  
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Tabela kluczowych gatunków

Species ReactivityKey ApplicationsHostFormatAntibody Type
HIHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberCBL85
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-Endothelin-1 Antibody, clone IC4
References
Product Information
FormatPurified
Control
  • Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells
PresentationLiquid in 0.02 M PBS with 0.25 M NaCl, pH 7.6. Contains 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect Endothelin-1 using this Anti-Endothelin-1 Antibody, clone IC4 validated for use in IHC.
Key Applications
  • Immunohistochemistry
Application NotesDevelopment of Immunoradiometric assay (IRMA) for endothelin ET-1 which as a circulating plasma peptide has been associated with a variety of disease studies such as diabetes, hypertension, cardiogenic shock, acute myocardial infarction and uraemia.

Suitable for immunohistochemistry on frozen sections

Optimal working dilutions must be determined by the end user.
Biological Information
CloneIC4
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
SpecificityRecognizes endothelin ET-1 (10% cross-reactivity with ET-3) and when used in conjunction with CBL87 (anti-endothelin C-terminus) has a sensitivity of 0.06 pmol/L for ET-1.
IsotypeIgG1
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • EDN1
  • OTTHUMP00000039245
  • Preproendothelin-1
  • ET1
  • PPET1
  • ET-1
  • HDLCQ7
Purification MethodProtein A Purfied
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P05305 # Endothelins are endothelium-derived vasoconstrictor peptides.
SIZE: 212 amino acids; 24425 Da
SUBCELLULAR LOCATION: Secreted.
TISSUE SPECIFICITY: Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.
SIMILARITY: SwissProt: P05305 ## Belongs to the endothelin/sarafotoxin family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsFor use within 1 month of purchase when stored at +4°C, for long-term storage, aliquot antibody into small volumes and store at -20°C.
Packaging Information
Material Size1 mg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numer katalogowy GTIN
CBL85 04053252336560

Documentation

Anti-Endothelin-1 Antibody, clone IC4 MSDS

Title

Safety Data Sheet (SDS) 

Anti-Endothelin-1 Antibody, clone IC4 Certificates of Analysis

TitleLot Number
MOUSE ANTI-HUMAN ENDOTHELIN 1 MONOCLONAL ANTIBODY 2919594
MOUSE ANTI-HUMAN ENDOTHELIN 1 MONOCLONAL ANTIBODY 2979566
MOUSE ANTI-HUMAN ENDOTHELIN 1 MONOCLONAL ANTIBODY 2953795
MOUSE ANTI-HUMAN ENDOTHELIN 1 MONOCLONAL ANTIBODY 2953796
MOUSE ANTI-HUMAN ENDOTHELIN 1 MONOCLONAL ANTIBODY 2924643
MOUSE ANTI-HUMAN ENDOTHELIN 1 MONOCLONAL ANTIBODY 3102352
MOUSE ANTI-HUMAN ENDOTHELIN 1 MONOCLONAL ANTIBODY - 2441921 2441921
MOUSE ANTI-HUMAN ENDOTHELIN 1 MONOCLONAL ANTIBODY - 2455690 2455690
MOUSE ANTI-HUMAN ENDOTHELIN 1 MONOCLONAL ANTIBODY - 2274267 2274267
MOUSE ANTI-HUMAN ENDOTHELIN 1 MONOCLONAL ANTIBODY - 2299128 2299128
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Data Sheet

Title
MOUSE ANTI-HUMAN ENDOTHELIN 1 MONOCLONAL ANTIBODY