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MAB4356 Anti-DPPA-2 Antibody, clone 6C1.2

This Anti-DPPA-2 Antibody, clone 6C1.2 is validated for use in WB for the detection of DPPA-2.

Anti-DPPA-2 Antibody, clone 6C1.2 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Stem Cell Research Research Sub-Category: Pluripotent & Early Differentiation Gene Symbol: PESCRG1 UniProt Number: Q7Z7J5
MAB4356
100 µg  
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Tabela kluczowych gatunków

Species ReactivityKey ApplicationsHostFormatAntibody Type
MWBMPurifiedMonoclonal Antibody
Description
Catalogue NumberMAB4356
DescriptionAnti-DPPA-2 Antibody, clone 6C1.2
Alternate Names
  • Pluripotent embryonic stem cell-related gene 1 protein
  • developmental pluripotency associated 2
Background InformationDPPA-2 (developmental pluripotency associated-2) is a novel Oct-4-related protein that is localized to the nucleus of mouse fetal germ cells. DPPA-2 has binding sites for both POU and Sox-2 protein domains and is expressed primarily in the developing germ line following gastrulation. These associations suggest that this protein participates in a very strong supportive role in maintaining cell pluripotentiality. In addition to its role as a pluripotency marker, more recent research using cancer cells suggests that DPPA-2 may also act as an embryo-cancer antigen—pointing to the presence of abnormal cell growth and the formation of cancerous cells.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4) and
150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-DPPA-2 Antibody, clone 6C1.2 is validated for use in WB for the detection of DPPA-2.
Key Applications
  • Western Blotting
Biological Information
ImmunogenFull length recombinant mouse DPPA-2 protein.
Clone6C1.2
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
SpecificityThis monoclonal antibody recognizes the mouse DPPA-2 protein.
IsotypeIgG2aκ
Species Reactivity
  • Mouse
Species Reactivity NoteReacts with mouse. Reactivity with other species has not been tested.
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • PESCRG1
Purification MethodProtein G Purified
UniProt Number
UniProt SummaryFUNCTION: May play a role in maintaining cell pluripotentiality.
SUBCELLULAR LOCATION: Nucleus.
TISSUE SPECIFICITY: Expressed in embryonic stem cells. No expression is seen in 5 months embryo, mesenchymal stem cells, embryonic fibrocytes and adult tissues.
SEQUENCE SIMILARITIES: Contains 1 SAP domain.
Stem Cell Type
  • Mouse Embryonic Stem Cells
Molecular Weight~34 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance(Based upon representative data from a previous lot).
Western Blotting: Recommended working concentration is 2 µg/mL.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numer katalogowy GTIN
MAB4356 04053252318283

Documentation

Anti-DPPA-2 Antibody, clone 6C1.2 MSDS

Title

Safety Data Sheet (SDS) 

Anti-DPPA-2 Antibody, clone 6C1.2 Certificates of Analysis

TitleLot Number
Anti-DPPA-2, clone 6C1.2 - 2018494 2018494
Anti-DPPA-2, clone 6C1.2 - 2513124 2513124
Anti-DPPA-2, clone 6C1.2 - 3217079 3217079
Anti-DPPA-2, clone 6C1.2 - 3240481 3240481
Anti-DPPA-2, clone 6C1.2 - 3430318 3430318
Anti-DPPA-2, clone 6C1.2 - NRG1633603 NRG1633603
Anti-DPPA-2, clone 6C1.2 -2685654 2685654
Anti-DPPA-2, clone 6C1.2 Monoclonal Antibody 3046689
Anti-DPPA-2, clone 6C1.2 Monoclonal Antibody 2943618
Anti-DPPA-2, clone 6C1.2 Monoclonal Antibody 2903964