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MABS421 Anti-DKK3, clone 4G7 Antibody

Anti-DKK3, clone 4G7 Antibody is an antibody against DKK3 for use in western blotting & flow cytometry.

Anti-DKK3, clone 4G7 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Cytoskeletal Signaling Gene Symbol: DKK3, REIC UniProt Number: Q9UBP4
MABS421
100 µL  
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Tabela kluczowych gatunków

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, FCMAscitesMonoclonal Antibody
Description
Catalogue NumberMABS421
DescriptionAnti-DKK3, clone 4G7 Antibody
Alternate Names
  • Dickkopf-related protein 3
  • Dickkopf-3
  • Dkk-3
  • hDkk-3
Background InformationDickkopf-related protein 3, also known as Dickkopf-3, or Dkk-3, or hDkk-3, and encoded by the gene DKK3/ REIC is a member of the dickkopf family. DKK3 is a 350 amino acid secreted glycoprotein that is composed of an N-terminal signal peptide and two conserved cysteine-rich domains, which are separated by a 12 amino acid linker region. This secreted protein is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene.
References
Product Information
FormatAscites
PresentationMouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-DKK3, clone 4G7 Antibody is an antibody against DKK3 for use in western blotting & flow cytometry.
Key Applications
  • Western Blotting
  • Flow Cytometry
Application NotesFlow Cytometry Analysis: A 1:200-400 dilution from a representative lot detected DKK3 in MCF-7 cells.
Biological Information
ImmunogenPurified recombinant fragment of human DKK3 expressed in E. Coli
Clone4G7
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
IsotypeIgG1
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Gene Symbol
  • DKK3
  • REIC
Purification MethodUnpurified
UniProt Number
Molecular Weight~44 kDa observed. Uncharacterized bands may be observed in some lysate(s).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in HEK293, MCF-7 and HL7702 cell lysates.

Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected DKK3 in HEK293, MCF-7 and HL7702 cell lysates.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numer katalogowy GTIN
MABS421 04053252955440