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AB3241-25UL Anti-Cdc2 Antibody, phospho-specific (Tyr15)

Use Anti-Cdc2 Antibody, phospho-specific (Tyr15) (Rabbit Polyclonal Antibody) validated in WB to detect Cdc2 also known as Cell Division Cycle 2, p34 Protein Kinase.

Anti-Cdc2 Antibody, phospho-specific (Tyr15) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Epigenetics & Nuclear Function Research Sub-Category: Cell Cycle, DNA Replication & Repair Gene Symbol: CDC2, CDK1, DKFZp686L20222, MGC111195, CDC28A, EC 2.7.11.22, EC 2.7.11.23 UniProt Number: P06493
AB3241-25UL
25 µL  
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Tabela kluczowych gatunków

Species ReactivityKey ApplicationsHostFormatAntibody Type
RWBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberAB3241-25UL
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-Cdc2 Antibody, phospho-specific (Tyr15)
Alternate Names
  • Cell Division Cycle 2
  • p34 Protein Kinase
  • Cyclin-dependent Kinase 1
References
Product Information
FormatAffinity Purified
PresentationAffinity purified immunoglobulin in 10 mM Hepes, pH 7.5, with 150 mM NaCl, 100 μg/mL BSA and 50% glycerol.
Quality LevelMQ100
Applications
ApplicationUse Anti-Cdc2 Antibody, phospho-specific (Tyr15) (Rabbit Polyclonal Antibody) validated in WB to detect Cdc2 also known as Cell Division Cycle 2, p34 Protein Kinase.
Key Applications
  • Western Blotting
Application NotesWestern blot: 1:1,000

Optimal working dilutions must be determined by the end user.
Biological Information
ImmunogenSynthetic peptide corresponding to amino acids surrounding the phosphoTry15 of human, rat, mouse and Xenopus CDC2.
Epitopephospho-specific (Tyr15)
HostRabbit
SpecificityCDC2, phosphoTyr15. By Western blot the antibody recognizes the ~35 kDa phospho CDC2 protein. The labeling of the CDC2 band in Western blots of rat brain is blocked by the phosphopeptide but not by the dephosphopeptide.
Species Reactivity
  • Rat
Antibody TypePolyclonal Antibody
Entrez Gene Number
Entrez Gene SummaryThe protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
Gene Symbol
  • CDC2
  • CDK1
  • DKFZp686L20222
  • MGC111195
  • CDC28A
  • EC 2.7.11.22
  • EC 2.7.11.23
Modifications
  • Phosphorylation
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P06493 # Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.
SIZE: 297 amino acids; 34095 Da
SUBUNIT: Forms a stable but non-covalent complex with a regulatory subunit and with a cyclin. Interacts with DLG7. Isoform 2 is unable to complex with cyclin B1 and also fails to bind to the CDK inhibitor p21. Interacts with catalytically active CCNB1 and RALBP1 during mitosis to form an endocytotic complex during interphase.
SUBCELLULAR LOCATION: Nucleus (By similarity).
SIMILARITY: SwissProt: P06493 ## Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. & Contains 1 protein kinase domain.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain at -20°C in undiluted for up to 6 months from date of receipt. Avoid repeated freeze/thaw cycles. Do not store in a self-defrosting freezer.
Packaging Information
Material Size25 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numer katalogowy GTIN
AB3241-25UL 04053252364747

Documentation

Anti-Cdc2 Antibody, phospho-specific (Tyr15) MSDS

Title

Safety Data Sheet (SDS) 

Anti-Cdc2 Antibody, phospho-specific (Tyr15) Certificates of Analysis

TitleLot Number
RABBIT ANTI-CDC2 phosphoTyr15 - 3308257 3308257
RABBIT ANTI-CDC2 phosphoTyr15 -2518458 2518458
RABBIT ANTI-CDC2 phosphoTyr15 -2581710 2581710
RABBIT ANTI-CDC2 phosphoTyr15 -2719860 2719860
RABBIT ANTI-CDC2 phosphoTyr15 -2749223 2749223
RABBIT ANTI-CDC2 phosphoTyr15 AFFINITY PURIFIED POLYCLONAL ANTIBODY 3082833
RABBIT ANTI-CDC2 phosphoTyr15 AFFINITY PURIFIED POLYCLONAL ANTIBODY 2975421
RABBIT ANTI-CDC2 phosphoTyr15 AFFINITY PURIFIED POLYCLONAL ANTIBODY 2928471
RABBIT ANTI-CDC2 phosphoTyr15 AFFINITY PURIFIED POLYCLONAL ANTIBODY 2903945
RABBIT ANTI-CDC2 phosphoTyr15 AFFINITY PURIFIED POLYCLONAL ANTIBODY 2884740
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