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AB3506P Anti-Arginine Vasopressin Receptor 1a Antibody

AB3506P
50 µg  
Purchase on Sigma-Aldrich

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Tabela kluczowych gatunków

Species ReactivityKey ApplicationsHostFormatAntibody Type
RELISA, WBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberAB3506P
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-Arginine Vasopressin Receptor 1a Antibody
Alternate Names
  • AVP R1a
  • V1a
References
Product Information
FormatAffinity Purified
HS Code3002 15 90
PresentationAffinity purified immunoglobulin. Liquid in PBS with 0.1% BSA.
Quality LevelMQ100
Applications
ApplicationAnti-Arginine Vasopressin Receptor 1a Antibody detects level of Arginine Vasopressin Receptor 1a & has been published & validated for use in ELISA & WB.
Key Applications
  • ELISA
  • Western Blotting
Application NotesWestern blot: 1-10 μg/mL using ECL.

ELISA: 0.5-1 μg/mL using 1 μg/mL control peptide per well.

Optimal working dilutions must be determined by the end user.
Biological Information
ImmunogenA 19 amino acid peptide sequence within the extracellular, N-terminal domain of rat AVR-V1a (Morel et al. 1992; Innamorti et al. 1996; Thibonnier et al. 1994; Hirasawa et al. 1994).
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityRecognizes rat Arginine Vasopressin Receptor V1a (AVR-V1a). The immunogen shows no significant sequence homology with AVR-V1b, AVR-V2 or AVR-V3.

SPECIES REACTIVITIES: The immunogen peptide is 84% conserved in mouse, 68% in human and 52% in sheep AVR-V1a. Reactivity with other species has not been confirmed.
Species Reactivity
  • Rat
Antibody TypePolyclonal Antibody
Entrez Gene Number
Entrez Gene SummaryThe protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis.
Gene Symbol
  • AVPR1A
  • AVPR1
  • V1aR
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P37288 # Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment.
SIZE: 418 amino acids; 46800 Da
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
SIMILARITY: SwissProt: P37288 ## Belongs to the G-protein coupled receptor 1 family.
MISCELLANEOUS: Differences in regional receptor expression in the brain as well as differences in social behavior may result from a highly variable repetitive sequence in the 5' flanking region of AVPR1A. One such allelic variant has been linked to autism.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size50 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numer katalogowy GTIN
AB3506P 04053252732454

Documentation

Anti-Arginine Vasopressin Receptor 1a Antibody MSDS

Title

Safety Data Sheet (SDS) 

Anti-Arginine Vasopressin Receptor 1a Antibody Certificates of Analysis

TitleLot Number
RABBIT ANTI-ARGININE VASOPRESSIN RECEPTOR V1a (AVR-V1a) AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2386476 2386476
RABBIT ANTI-ARGININE VASOPRESSIN RECEPTOR V1a (AVR-V1a) AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2398811 2398811
RABBIT ANTI-ARGININE VASOPRESSIN RECEPTOR V1a (AVR-V1a) AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2449213 2449213
RABBIT ANTI-ARGININE VASOPRESSIN RECEPTOR V1a (AVR-V1a) -2763869 2763869
RABBIT ANTI-ARGININE VASOPRESSIN RECEPTOR V1a (AVR-V1a) AFFINITY PURIFIED - 3474141 3474141
RABBIT ANTI-ARGININE VASOPRESSIN RECEPTOR V1a (AVR-V1a) AFFINITY PURIFIED POLYCLONAL ANTIBODY 2972456
RABBIT ANTI-ARGININE VASOPRESSIN RECEPTOR V1a (AVR-V1a) AFFINITY PURIFIED POLYCLONAL ANTIBODY 2966795
RABBIT ANTI-ARGININE VASOPRESSIN RECEPTOR V1a (AVR-V1a) AFFINITY PURIFIED POLYCLONAL ANTIBODY 2865347
RABBIT ANTI-ARGININE VASOPRESSIN RECEPTOR V1a (AVR-V1a) AFFINITY PURIFIED POLYCLONAL ANTIBODY 2884749

References

Reference overviewPub Med ID
Receptor for Advanced Glycation End-Products Signaling Interferes with the Vascular Smooth Muscle Cell Contractile Phenotype and Function.
Simard, E; Söllradl, T; Maltais, JS; Boucher, J; D'Orléans-Juste, P; Grandbois, M
PloS one  10  e0128881  2015

Pokaż streszczenie
26248341 26248341

Data Sheet

Title
RABBIT ANTI-ARGININE VASOPRESSIN RECEPTOR V1a (AVR-V1a) AFFINITY PURIFIED POLYCLONAL ANTIBODY