pigment+epithelium Search Results

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			96-Well Plate

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	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

Effect of quiescence on integrin alpha5beta1 expression in human retinal pigment epithelium.
PURPOSE: The retinal pigment epithelium (RPE) is differentiated and mitotically inactive in the normal eye, but several pathologies such as proliferative vitreoretinopathy (PVR) cause RPE cells to dedifferentiate and resume proliferation. Integrins, a family of cell surface glycoproteins that mediate cell proliferation and diffe...
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Múltiplo
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Múltiplo
Visual cycle protein RPE65 persists in new retinal cells during retinal regeneration of adult newt.
Adult newts can regenerate their entire retina through transdifferentiation of the retinal pigment epithelium (RPE). The objective of this study was to redescribe the retina regeneration process by means of modern biological techniques. We report two different antibodies (RPE-No.112 and MAB5428) that recognize the newt homolog o...
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MAB5428
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Anti-Retinal Pigment Epithelium 65 Antibody
Histopathology and functional correlations in a patient with a mutation in RPE65, the gene for retinol isomerase.
Here the authors describe the structural features of the retina and retinal pigment epithelium (RPE) in postmortem donor eyes of a 56-year-old patient with a homozygous missense RPE65 mutation (Ala132Thr) and correlate the pathology with the patient's visual function last measured at age 51.Eyes were enucleated within 13.5 hours...
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Múltiplo
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Múltiplo
Structural and functional characterization of recombinant human cellular retinaldehyde-binding protein.
Cellular retinaldehyde-binding protein (CRALBP) is abundant in the retinal pigment epithelium (RPE) and Müller cells of the retina where it is thought to function in retinoid metabolism and visual pigment regeneration. The protein carries 11-cis-retinal and/or 11-cis-retinol as endogenous ligands in the RPE and retina and mutati...
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13-110
Nombre del producto:

MBP, Dephosphorylated
Divergent requirements for fibroblast growth factor signaling in zebrafish maxillary barbel and caudal fin regeneration.
The zebrafish maxillary barbel is an integumentary organ containing skin, glands, pigment cells, taste buds, nerves, and endothelial vessels. The maxillary barbel can regenerate (LeClair & Topczewski 2010); however, little is known about its molecular regulation. We have studied fibroblast growth factor (FGF) pathway molecul...
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AB5054
Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signaling.
In phagocytic cells, including the retinal pigment epithelium (RPE), acidic compartments of the endolysosomal system are regulators of both phagocytosis and autophagy, thereby helping to maintain cellular homeostasis. The acidification of the endolysosomal system is modulated by a proton pump, the V-ATPase, but the mechanisms th...
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MABC32
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Anti-p62 (Sequestosome-1) Antibody, clone 11C9.2
Localization of pigment epithelium derived factor (PEDF) in developing and adult human ocular tissues.
PURPOSE: To localize pigment epithelium-derived factor (PEDF) in developing and adult human ocular tissues. METHODS: PEDF was localized in fetal and adult eyes by immunofluorescence with a polyclonal antibody (pAb) against amino acids 327-343 of PEDF, or a monoclonal antibody (mAb) against the C-terminal 155 amino acids of PEDF....
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Múltiplo
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Múltiplo
Assays for the antiangiogenic and neurotrophic serpin pigment epithelium-derived factor.
Pigment epithelium-derived factor (PEDF) is a secreted serpin that exhibits a variety of interesting biological activities. The multifunctional PEDF has neurotrophic and antiangiogenic properties, and acts in retinal differentiation, survival, and maintenance. It is also antitumorigenic and antimetastatic, and has stem cell self...
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MAB1059
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Anti-Pigment Epithelium Derived Factor Antibody, clone 10F12.2
Tauroursodeoxycholic acid (TUDCA) protects photoreceptors from cell death after experimental retinal detachment.
Detachment of photoreceptors from the underlying retinal pigment epithelium is seen in various retinal disorders such as retinal detachment and age-related macular degeneration and leads to loss of photoreceptors and vision. Pharmacologic inhibition of photoreceptor cell death may prevent this outcome. This study tests whether s...
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MAB1435
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Anti-Macrophages/Monocytes Antibody, clone ED-1
Pigment epithelium-derived factor is an intrinsic antifibrosis factor targeting hepatic stellate cells.
The liver is the major site of pigment epithelium-derived factor (PEDF) synthesis. Recent evidence suggests a protective role of PEDF in liver cirrhosis. In the present study, immunohistochemical analyses revealed lower PEDF levels in liver tissues of patients with cirrhosis and in animals with chemically induced liver fibrosis....
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AB5694

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Tipo de documento

Effect of quiescence on integrin alpha5beta1 expression in human retinal pigment epithelium.

Visual cycle protein RPE65 persists in new retinal cells during retinal regeneration of adult newt.

Histopathology and functional correlations in a patient with a mutation in RPE65, the gene for retinol isomerase.

Structural and functional characterization of recombinant human cellular retinaldehyde-binding protein.

Divergent requirements for fibroblast growth factor signaling in zebrafish maxillary barbel and caudal fin regeneration.

Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signaling.

Localization of pigment epithelium derived factor (PEDF) in developing and adult human ocular tissues.

Assays for the antiangiogenic and neurotrophic serpin pigment epithelium-derived factor.

Tauroursodeoxycholic acid (TUDCA) protects photoreceptors from cell death after experimental retinal detachment.

Pigment epithelium-derived factor is an intrinsic antifibrosis factor targeting hepatic stellate cells.

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