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233155 Cleland’s Reagent - CAS 3483-12-3 - Calbiochem

Descripción

Replacement Information

Tabla espec. clave

CAS #Empirical Formula
3483-12-3C₄H₁₀O₂S₂

Precios y disponibilidad

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233155-25GM
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      Frasco de vidrio 25 gm
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      233155-5GM
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      Ingrese cantidad 
      Suspendido
      Cantidades limitadas disponibles
      Debe confirmarse disponibilidad
        El resto: se avisará
          El resto: se avisará
          Se avisará
          Póngase en contacto con el Servicio de Atención al Cliente
          Contact Customer Service

          Ampolla de plást. 5 gm
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          Description
          OverviewA protective agent for SH groups. Cyclizes as it reduces disulfides to thiols, so reaction is "driven" to completion. Does not contain waxy surfactant found in many other preparations.
          Oxidized dithiothreitol: ≤0.5%.
          Catalogue Number233155
          Brand Family Calbiochem®
          SynonymsDithiothreitol, DTT
          References
          ReferencesGailis, L. 1994. Eur. J. Pharmacol. 292, 39.
          Lauriault, V.V.M., and O'Brien, P.J. 1991. Mol. Pharmacol. 40, 125.
          Klonne, D.R., and Johnson, D.R. 1988. Toxicol. Lett. 42, 199.
          Zahler, W.L., and Cleland, W.W. 1968. J. Biol. Chem. 243, 716.
          Cleland, W.W. 1964. Biochemistry 3, 480.
          Product Information
          CAS number3483-12-3
          FormWhite to off-white powder
          Hill FormulaC₄H₁₀O₂S₂
          Chemical formulaC₄H₁₀O₂S₂
          Quality LevelMQ100
          Applications
          Biological Information
          Purity≥97% by titration
          Physicochemical Information
          ContaminantsHeavy metals: ≤1 ppm
          Heavy metals<1 ppm
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSEK1610000
          Safety Information
          R PhraseR: 22-36/38

          Harmful if swallowed.
          Irritating to eyes and skin.
          S PhraseS: 36-26

          Wear suitable protective clothing.
          In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Harmful
          Storage +2°C to +8°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot, purge with inert gas, and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          Número de referencia GTIN
          233155-25GM 04055977217711
          233155-5GM 04055977217728

          Documentation

          Cleland’s Reagent - CAS 3483-12-3 - Calbiochem Ficha datos de seguridad (MSDS)

          Título

          Ficha técnica de seguridad del material (MSDS) 

          Cleland’s Reagent - CAS 3483-12-3 - Calbiochem Certificados de análisis

          CargoNúmero de lote
          233155

          Referencias bibliográficas

          Visión general referencias
          Gailis, L. 1994. Eur. J. Pharmacol. 292, 39.
          Lauriault, V.V.M., and O'Brien, P.J. 1991. Mol. Pharmacol. 40, 125.
          Klonne, D.R., and Johnson, D.R. 1988. Toxicol. Lett. 42, 199.
          Zahler, W.L., and Cleland, W.W. 1968. J. Biol. Chem. 243, 716.
          Cleland, W.W. 1964. Biochemistry 3, 480.

          Folleto

          Cargo
          Bulk Product Guide
          Ficha técnica

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision29-April-2008 RFH
          SynonymsDithiothreitol, DTT
          DescriptionDTT is a water-soluble protective reagent for sulfhydryl groups. It maintains monothiols in the reduced state and reduces disulfides quantitatively. Most widely used for the study of disulfide exchange reactions of protein disulfides. DTT readily permeates cell membranes. Protects protein sulfhydryls and restores enzyme activity lost by the oxidation of sulfhydryl groups in vitro. As a reducing agent, it cyclizes as it reduces disulfides to thiols, so the reaction is "driven" to completion without using large excesses of reductant. If free thiols are to be assayed later, excess reductant must be removed by dialysis or some other appropriate method. Alternatively, an immobilized form of DTT (REDUCTACRYL Reagent, Cat. No. 233157) can be used. Oxidized dithiothreitol: ≤0.5%.
          FormWhite to off-white powder
          Intert gas (Yes/No) Packaged under inert gas
          CAS number3483-12-3
          RTECSEK1610000
          Chemical formulaC₄H₁₀O₂S₂
          Purity≥97% by titration
          ContaminantsHeavy metals: ≤1 ppm
          SolubilityEthanol or H₂O (30 mg/ml)
          Storage +2°C to +8°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot, purge with inert gas, and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Harmful
          Merck USA index14, 3376
          ReferencesGailis, L. 1994. Eur. J. Pharmacol. 292, 39.
          Lauriault, V.V.M., and O'Brien, P.J. 1991. Mol. Pharmacol. 40, 125.
          Klonne, D.R., and Johnson, D.R. 1988. Toxicol. Lett. 42, 199.
          Zahler, W.L., and Cleland, W.W. 1968. J. Biol. Chem. 243, 716.
          Cleland, W.W. 1964. Biochemistry 3, 480.