CD11b Antibodies
Millipore offers CD11B (Integrin αM) antibodies, which demonstrates specificity and are validated. See below for a list of antibodies for CD11B, based on the expertise of Upstate & Chemicon.
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CD11b Antibodies
CD11b is the 165 kDa α-chain of the Mac-1 complex. It functions as a cell surface receptor for the C3bi complement fragment. There is evidence that CD11b can bind fibrinogen in addition to C3bi. Two binding sites have now been reported, one recognizing lipopolysaccharide, and the other protein ligands containing the arg-gly-asp sequence. Binding of the coagulation factor X has also been suggested as an additional receptor role of CD11b. This protein belongs to a family of related proteins designated CD11 in the classification system for human leucocyte differentiation antigens, which shares a common β-chain with a MW of 95 kDa (CD18).