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484235 p-Nitroblue Tetrazolium Chloride - CAS 298-83-9 - Calbiochem

p-Nitroblue Tetrazolium Chloride, CAS 298-83-9, is a NADPH-diaphorase substrate that competitively inhibits nitric oxide synthase (IC50 = 3-4 µM). A well-known scavenger of superoxide anions.

p-Nitroblue Tetrazolium Chloride - CAS 298-83-9 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: NBT, Nitro BT

Primary Target: NOS
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484235
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Overview

Key Spec Table

CAS #Empirical Formula
298-83-9C₄₀H₃₀Cl₂N₁₀O₆

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      Description
      OverviewNADPH-diaphorase substrate that competitively inhibits nitric oxide synthase (IC50 = 3-4 µM). A well-known scavenger of superoxide anions. Useful as a substrate for alkaline phosphatase, often in conjunction with BCIP (Cat. No. 203788).
      Catalogue Number484235
      Brand Family Calbiochem®
      SynonymsNBT, Nitro BT
      References
      ReferencesPistelli, A., et al. 1994. Biochem. Pharmacol. 47, 1737.
      De la Fuente, M., et al. 1993. Comp. Immunol. Microbiol. Infect. Dis. 16, 29.
      Libon, C., et al. 1993. J. Leukoc. Biol. 53, 93.
      Mittal, C.K. 1993. Biochem. Biophys. Res. Commun. 193, 126.
      Nichols, K., et al. 1992. Neuroscience 51, 791.
      Nichols, K., et al. 1992. Neuroscience 51, 791.
      Product Information
      CAS number298-83-9
      FormYellow crystalline solid
      Hill FormulaC₄₀H₃₀Cl₂N₁₀O₆
      Chemical formulaC₄₀H₃₀Cl₂N₁₀O₆
      Hygroscopic Hygroscopic
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Applicationp-Nitroblue Tetrazolium Chloride, CAS 298-83-9, is a NADPH-diaphorase substrate that competitively inhibits nitric oxide synthase (IC50 = 3-4 µM). A well-known scavenger of superoxide anions.
      Biological Information
      Primary TargetNOS
      Primary Target IC<sub>50</sub>3-4 µM
      Purity≥98% by TLC
      Safety Information according to GHS
      RTECSXF8045000
      Safety Information
      R PhraseR: 20/21/22-68

      Harmful by inhalation, in contact with skin and if swallowed.
      Possible risks of irreversible effects.
      S PhraseS: 22-26-36/37

      Do not breathe dust.
      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing and gloves.
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage.
      Global Trade Item Number
      Catalogue Number GTIN
      484235-250MG 04055977200690