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109253 Papanicolaou's solution 1a Harris' hematoxylin solution

for cytology

Papanicolaou's solution 1a Harris' hematoxylin solution MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Hematoxylin solution acc. to Harris, Colour solution acc. to Papanicolaou, Harris' Hematoxylin solution

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109253
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      1092531000
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          1092531022
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              1092532500
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                  PE11092531022/20
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                      		 1 l
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                      Description
                      Catalogue Number109253
                      SynonymsHematoxylin solution acc. to Harris, Colour solution acc. to Papanicolaou, Harris' Hematoxylin solution
                      DescriptionPapanicolaou’s solution 1a Harris hematoxylin solution
                      OverviewPapanicolaou’s solution 1a Harris hematoxylin solution - for cytology, is a ready-to-use solution used for human-medical cell diagnosis and serve the purpose of the cytological investigation of sample material of human origin, for example, gynecological and clinico-cytological specimen materials. Papanicolaou’s technique is the most used staining procedure for cytological specimen is and is intended for the the staining of exfoliative cells in cytological specimens. In the first step, the cell nuclei are stained either progressively or regressively with a hematoxylin solution, (Hematoxylin solution modified acc.to Gill II, (Cat.no. 105175), Papanicolaou’s solution 1a Harris hematoxylin solution, (Cat.no. 109253) or Papanicolaou’s solution 1b Hematoxylin solution S, (Cat.no. 109254)). Nuclei are stained blue to dark violet. In the progressive hematoxylin staining method, staining is carried out to the endpoint, after which the slide is blued in tapwater. With the regressive method the material is over-stained and the excess of staining solution is removed by acid rinsing steps, followed by the bluing step. The structures of nuclei are more differentiated and better visible by the regressive method. The second staining step is cytoplasmic staining by (Papanicolaou’s solution 2b Orange II solution, (Cat. no. 1106887) or Papanicolaou’s solution 2a Orange G solution (OG6), (Cat. no. 106888)), especially for demonstration of mature and keratinized cells. The target structures are stained orange in different intensities. In the third staining step is used the so-called polychrome solution, a mixture of eosin, light green SF and Bismarck brown, Papanicolaou’s solution 3a polychromatic solution EA 31, (Cat.no 109271), Papanicolaou’s solution 3b polychromatic solution EA 50, (Cat.no. 109272), Papanicolaou’s solution 3c polychromatic solution EA 65,(Cat.no. 109270), or Papanicolaou’s solution 3d polychromatic solution EA 65, (Cat.no.109269). The polychrome solution is used for demonstration of differentiation of squamous cells. Both Papanicolaou’s solution 1a Harris hematoxylin solution(Cat.no. 109253) and Papanicolaou’s solution 1b Hematoxylin solution S (Cat.no. 109254) give a blue to dark violet staining result with clinical specimen material.
                      A 500 ml bottle of either solution is sufficient for 1500 -2500 stainings. It is registered as IVD and CE certified product and can be used for clinical diagnostics. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.
                      References
                      Product Information
                      HS Code3212 90 00
                      Quality LevelMQ400
                      Applications
                      Applicationfor cytology
                      Biological Information
                      Physicochemical Information
                      Boiling point100 °C (1013 hPa)
                      Density1.04 g/cm3 (20 °C)
                      pH value2.5 - 3.0 (H₂O, 20 °C)
                      Dimensions
                      Materials Information
                      Toxicological Information
                      Safety Information according to GHS
                      Hazard Pictogram(s) Hazard Pictogram(s)
                      Hazard Statement(s)H318: Causes serious eye damage.
                      EUH210: Safety data sheet available on request.
                      Precautionary Statement(s)P280: Wear eye protection/ face protection.
                      P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
                      Signal WordDanger
                      Storage class10 - 13 Other liquids and solids
                      WGKWGK 1 slightly hazardous to water
                      Disposal28
                      Aqueous solutions: Container D.
                      Safety Information
                      Product Usage Statements
                      Storage and Shipping Information
                      StorageStore at +15°C to +25°C.
                      Packaging Information
                      Transport Information
                      Supplemental Information
                      Specifications
                      Suitability for microscopy (Vaginal smear)passes test
                      Nucleiblue to dark violet
                      Cyanophilic Cytoplasm (basophilic)blue-green
                      Eosinophilic Cytoplasm (acidophilic)pink
                      Global Trade Item Number
                      Catalogue Number GTIN
                      1092530500 04022536112466
                      1092531000 04022536676661
                      1092531022 04022536707433
                      1092532500 04022536112480
                      PE11092531022/20 04061839350892

                      Documentation

                      Papanicolaou's solution 1a Harris' hematoxylin solution SDS

                      Title

                      Safety Data Sheet (SDS) 

                      Papanicolaou's solution 1a Harris' hematoxylin solution Certificates of Analysis

                      Product Number PackagingSpecificationLot Number
                      1092530500 Plastic bottlePDF Specification Document
                      1092531000 Plastic bottlePDF Specification Document
                      1092531022 Plastic bottlePDF Specification Document
                      1092532500 Plastic bottlePDF Specification Document
                      PE11092531022/20 PDF Specification Document

                      User Guides

                      Title
                      109253 Solución de Papanicolaou 1a solución de hematoxilina según Harris para citología
                      109253 Solución de Papanicolaou 1a solución de hematoxilina según Harris para citología (versión de Cuba)
                      User Guide (IFU) - 109253

                      Related Products & Applications

                      Accessories (Primary)

                      Catalogue Number Description  
                      106887 Papanicolaou’s solution 2b Orange II solution Show Pricing & Availability
                      106888 Papanicolaou's solution 2a Orange G solution (OG 6) Show Pricing & Availability
                      109272 Papanicolaou's solution 3b polychromatic solution EA 50 Show Pricing & Availability
                      115938 Hematoxylin monohydrate (C.I.75290) Show Pricing & Availability

                      Accessories (Secondary)

                      Catalogue Number Description  
                      104302 Hematoxylin cryst. (C.I. 75290) Show Pricing & Availability
                      105175 Hematoxylin solution modified acc. to Gill II Show Pricing & Availability
                      106887 Papanicolaou’s solution 2b Orange II solution Show Pricing & Availability
                      106888 Papanicolaou's solution 2a Orange G solution (OG 6) Show Pricing & Availability
                      109272 Papanicolaou's solution 3b polychromatic solution EA 50 Show Pricing & Availability

                      Related Products By: Application Facete

                      Clinical Cytology
                      Cytodiagnosis
                      Papanicolaou

                      Categories

                      IVD/OEM Materials & Reagents > Microscopy > Cytology > Cytological Staining Reagents