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324875 Eicosapentaenoic Acid - CAS 10417-94-4 - Calbiochem

324875
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Overview

Key Spec Table

CAS #Empirical Formula
10417-94-4C₂₀H₃₀O₂

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324875-25MG
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      Glass bottle 25 mg
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      Description
      OverviewCell permeable. Shown to have a beneficial effect in cardiovascular diseases and inflammation. Causes elevation of intracellular free Ca2+. Inhibits 5-lipoxygenase and reduces thromboxane A2 production and blood viscosity. Reported to induce apoptosis in pancreatic cancer cell lines and to inhibit liver metastasis.
      Catalogue Number324875
      Brand Family Calbiochem®
      SynonymsEPA, 5,8,11,14,17-Eicosapentaenoic Acid, C20:5 ω-3
      References
      ReferencesIwamoto, S., et al. 1998. Nutr. Cancer 31, 143.
      Lai, P.B., et al. 1996. Br. J. Cancer 74, 1375.
      Marotta, F., et al. 1995. Digestion 56, 46. Kurihara, T., et al. 1994. Clin. Ther. 16, 830.
      Okuda, Y., et al. 1994. Biochem. Med. Metab. Biol. 51, 166.
      James, M.J., et al. 1993. J. Exp. Med. 178, 2261.
      chamcock, J.S., et al. 1992. Mol. Cell. Biochem. 116, 19.
      Stenson, W.F., et al. 1992. Ann. Intern. Med. 116, 609.
      Product Information
      CAS number10417-94-4
      ATP CompetitiveN
      FormClear liquid
      Hill FormulaC₂₀H₃₀O₂
      Chemical formulaC₂₀H₃₀O₂
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Primary Target5-lipoxygenase
      Purity≥99% by GC
      Physicochemical Information
      Cell permeableY
      Safety Information according to GHS
      RTECSJX3820000
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      Catalogue Number GTIN
      324875-25MG 04055977215847