Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

554720 trans-Retinoic Acid - CAS 302-79-4 - Calbiochem

Potent modulator of growth and differentiation. Inhibits melanocyte adhesion, motility, and growth.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Tretinoin, ATRA, Vitamin A Acid

View Products on Sigmaaldrich.com
554720
Purchase on Sigma-Aldrich

Overview

Key Spec Table

CAS #Empirical Formula
302-79-4C₂₀H₂₈O₂

Products

Catalogue NumberPackaging Qty/Pack
554720-500MG Glass bottle 500 mg
Add To Favorites
Description
OverviewPotent modulator of growth and differentiation. Exerts its effects by binding to nuclear retinoic acid receptors (RARs) which directly regulate gene expression. Inhibits melanocyte adhesion, motility, and growth. Has keratolytic activity. Induces differentiation of tumor cells of neural origin. Induces apoptosis in acute promyelocytic carcinoma cells. PROTECT FROM AIR.
Catalogue Number554720
Brand Family Calbiochem®
SynonymsTretinoin, ATRA, Vitamin A Acid
References
ReferencesTosi, P., et al. 1994. Leuk. Lymphoma 14, 503.
Clagett-Dame, M., et al. 1993. Arch. Biochem. Biophys. 300, 684.
Labbaye, C., et al. 1993. Blood 81, 475.
Sakashita, A., et al. 1993. Blood 81, 1009.
Situ, R., et al. 1993. Dermatology 186, 38.
Tini, M., et al. 1993. Genes Develop. 7, 295.
Leid, M., et al. 1992. Trends Biochem. Sci. 17, 427.
Sharpe, C.R. 1991. Neuron 7, 239.
Thaller, C. and Eichele, G. 1990. Nature 345, 815.
Product Information
CAS number302-79-4
FormYellow solid
Hill FormulaC₂₀H₂₈O₂
Chemical formulaC₂₀H₂₈O₂
Hygroscopic Hygroscopic
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Purity≥95% by assay
Safety Information according to GHS
RTECSVH6475000
Safety Information
R PhraseR: 22-36/37/38-63

Harmful if swallowed.
Irritating to eyes, respiratory system and skin.
Possible risk of harm to the unborn child.
S PhraseS: 22-26-36

Do not breathe dust.
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful & Carcinogenic / Teratogenic
Storage +2°C to +8°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). DMSO stock solutions are stable for up to 2 weeks at 4°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Global Trade Item Number
Catalogue Number GTIN
554720-500MG 04061838431332