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14-678M WNK2 Protein, active, 250 µg

Active, N-terminal 6His-tagged, recombinant, human WNK2, amino acids 166-489, for use in Kinase Assays.

14-678M
250 µg  Also available in 10 μg size (cat#14-678) and in bulk (cat#14-678-K).
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Catalogue Number14-678M
Brand Family Upstate
Trade Name
  • Upstate
DescriptionWNK2 Protein, active, 250 µg
OverviewN-terminal 6His-tagged, recombinant, human WNK2, amino acids 166-489
References
Product Information
Quality LevelMQ300
Applications
ApplicationActive, N-terminal 6His-tagged, recombinant, human WNK2, amino acids 166-489, for use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
Sourceexpressed by baculovirus in Sf21 cells
Entrez Gene Number
Entrez Gene SummaryThe protein encoded by this gene is a cytoplasmic serine-threonine kinase that contains cysteine in place of the lysine found at the conserved ATP-binding location in subdomain II of protein kinases. Since this protein does have kinase activity, it is possible that another lysine in the kinase subdomain I can substitute for the missing conserved lysine.
Gene Symbol
  • WNK2
  • NY-CO-43
  • SDCCAG43
  • P/OKcl.13
  • PRKWNK2
  • KIAA1760
  • PRK
Protein TargetWNK2
Purification MethodNi2+/NTA-agarose
Target Sub-FamilySTE
UniProt Number
UniProt SummaryCOFACTOR: Magnesium (By similarity).
SIZE: 2297 amino acids; 242676 Da
TISSUE SPECIFICITY: Predominantly expressed in heart, brain and colon.
SIMILARITY: SwissProt: Q9Y3S1 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WNK subfamily. & Contains 1 protein kinase domain.
Molecular Weight41.2kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated by phosphorylation of myelin basic protein (Catalog # 13-104)
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 6 months at -70°C from date of shipment
Packaging Information
Material Size250 µg
Material PackageAlso available in 10 μg size (cat#14-678) and in bulk (cat#14-678-K).
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
14-678M 04055977305333

Documentation

Related Products & Applications

Alternative Packsize

Catalogue Number Description
14-678 WNK2 Protein, active, 10 µg

Product Families

Kinase & Phosphatase Products

Millipore offers a large portfolio of Kinases, Phophatases, Substrates, Inhibitors, Kits, reagents & tools for Signaling research. See below for a list of these products, in multiple pack sizes.
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Categories

Life Science Research > Proteins and Enzymes > Purified Kinases
Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases