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676474 VEGF₁₆₄, Mouse, Recombinant, S. frugiperda

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676474
  
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Overview

Replacement Information

Key Spec Table

Purity
≥95% by SDS-PAGE
Description
Overview

This product has been discontinued.



Recombinant, mouse VEGF164 (164-amino acid splice variant of VEGF) expressed in S. frugiperda insect cells. The most abundant form in mice, VEGF164 is a potent angiogenic factor and vascular permeability factor in vivo, as well as a chemoattractant for monocytes and endothelial cells. Forms a biologically active homodimer and evidence suggests that it is also biologically active as a heterodimer with other VEGF splice variants. Expression of VEGF164 appears to be essential for normal bone development and vascularization.

Catalogue Number676474
Brand Family Calbiochem®
SynonymsVascular Endothelial Growth Factor₁₆₄
References
ReferencesMaes, C., et al. 2002. Mech. Dev. 111, 61.
Grunstein, J., et al. 2000. Mol. Cell Biol. 20, 7282.
Springer, M.L., et al. 2000. J. Gene Med. 2, 279.
Product Information
FormLyophilized solid
Quality LevelMQ100
Applications
Biological Information
Biological activityED₅₀ ≥1 ng/ml as measured by the stimulation of ³H-thymidine incorporation by human umbilical vein endothelial cells and bovine aortic endothelial cells. In vivo effects using the 13-day-old chick chorioallantoic membrane (CAM) assay can be seen between 0.5-4 µg
Purity≥95% by SDS-PAGE
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 3 months at -70°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
676474 0

Documentation

VEGF₁₆₄, Mouse, Recombinant, S. frugiperda SDS

Title

Safety Data Sheet (SDS) 

VEGF₁₆₄, Mouse, Recombinant, S. frugiperda Certificates of Analysis

TitleLot Number
676474

References

Reference overview
Maes, C., et al. 2002. Mech. Dev. 111, 61.
Grunstein, J., et al. 2000. Mol. Cell Biol. 20, 7282.
Springer, M.L., et al. 2000. J. Gene Med. 2, 279.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision16-September-2008 RFH
SynonymsVascular Endothelial Growth Factor₁₆₄
DescriptionRecombinant, mouse VEGF164 (164-amino acid splice variant of VEGF) expressed in S. frugiperda insect cells. It is the most abundant form of VEGF found in mice. VEGF164 is a potent angiogenic factor and vascular permeability factor in vivo, as well as a chemoattractant for monocytes and endothelial cells. Forms a biological active homodimer. Evidence also suggests that it is biologically active as a heterodimer with other VEGF splice variants.
FormLyophilized solid
Purity≥95% by SDS-PAGE
Biological activityED₅₀ ≥1 ng/ml as measured by the stimulation of ³H-thymidine incorporation by human umbilical vein endothelial cells and bovine aortic endothelial cells. In vivo effects using the 13-day-old chick chorioallantoic membrane (CAM) assay can be seen between 0.5-4 µg
SolubilityReconstitute in PBS or 50 mM acetic acid to a concentration ≥ 100 ng/µl.
Storage ≤ -70°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 3 months at -70°C.
Toxicity Standard Handling
ReferencesMaes, C., et al. 2002. Mech. Dev. 111, 61.
Grunstein, J., et al. 2000. Mol. Cell Biol. 20, 7282.
Springer, M.L., et al. 2000. J. Gene Med. 2, 279.