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GF113 Transforming Growth Factor-β2 Protein, Recombinant human

Transforming Growth Factor-beta2 (TGF-beta2) is a member of a superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation & differentiation of normal & transformed cells.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Key Applications: Cell Culture UniProt Number: P61812 Entrez Gene Number: NM_003238.1
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GF113
10 µg  
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Key Spec Table

Key ApplicationsSpeciesSourcePurity
CULTHuman Baculovirus infected High-5 cellsGreater than 95% by SDS-PAGE. Endotoxin level is less than 0.1 ng per μg (1EU/ug) of TGF-Beta2.
Description
Catalogue NumberGF113
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionTransforming Growth Factor-β2 Protein, Recombinant human
OverviewTransforming Growth Factor- beta2 (TGF-beta2) is a member of a superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation and differentiation of normal and transformed cells. Human TGF-beta2 is a 25.0 kDa protein with each subunit containing 112 amino acid residues.
Alternate Names
  • TGF-beta2
References
Product Information
HS Code3504 00 19
PresentationLyophilized from Sodium Citrate, pH 3.5.
Quality LevelMQ100
Applications
ApplicationTransforming Growth Factor-beta2 (TGF-beta2) is a member of a superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation & differentiation of normal & transformed cells.
Key Applications
  • Cell Culture
Biological Information
PurityGreater than 95% by SDS-PAGE. Endotoxin level is less than 0.1 ng per μg (1EU/ug) of TGF-Beta2.
SourceBaculovirus infected High-5 cells
Specific ActivityDetermined by its ability to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells. The ED(50) was found to be <=0.2ng/ml, corresponding to a specific activity of >=5 x 10e6 units/mg.
Entrez Gene Number
Gene Symbol
  • TGFB2
  • Polyergin
  • G-TSF
  • TGF-beta-2
  • MGC116892
  • TGF-beta2
  • Cetermin
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P61812 # TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth.
SIZE: 414 amino acids; 47748 Da
SUBUNIT: Homodimer; disulfide-linked.
SUBCELLULAR LOCATION: Secreted.
DISEASE: SwissProt: P61812 # A chromosomal aberration involving TGFB2 is found in a family with Peters anomaly [MIM:604229]. Translocation t(1;7)(q41;p21) with HDAC9. Peters anomaly consists of a central corneal leukoma, absence of the posterior corneal stroma and Descemet membrane, and a variable degree of iris and lenticular attachments to the central aspect of the posterior cornea.
SIMILARITY: SwissProt: P61812 ## Belongs to the TGF-beta family.
Stem Cell Type
  • Mesenchymal Stem Cells
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsThe lyophilized powder is stable for a few weeks at room temperature, but best stored at -20°C. Reconstitute with water to a concentration of 50 μg/ml (e.g., 5 μg/100 μl), this will yield a solution of 1 mM citrate buffer pH 3.5 This solution can then be stored at room temperature or at 2-8ºC for 1 month. It is recommended that further dilutions be made into PBS containing 2 mg/ml albumin and stored at -20ºC. Reconstituted human TGF-beta2 should be stored in undiluted aliquots at -20°C for at least 2 months. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size10 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
GF113 04053252733925

Documentation

Transforming Growth Factor-β2 Protein, Recombinant human SDS

Title

Safety Data Sheet (SDS) 

Transforming Growth Factor-β2 Protein, Recombinant human Certificates of Analysis

TitleLot Number
R RE EC CO OM MB BI IN NA AN NT T H HU UM MA AN N T TR RA AN NS SF FO OR RM MI IN NG G G GR RO OW WT TH H F FA AC CT TO OR R-β β2 2 3069346
RECOMBINANT HUMAN TRANSFORMING GROWTH FACTOR -#946;2 - 2151828 2151828
RECOMBINANT HUMAN TRANSFORMING GROWTH FACTOR - β2 - 3746869 3746869
RECOMBINANT HUMAN TRANSFORMING GROWTH FACTOR - β2 - 4163720 4163720
RECOMBINANT HUMAN TRANSFORMING GROWTH FACTOR-2 - 2326311 2326311
RECOMBINANT HUMAN TRANSFORMING GROWTH FACTOR-β 2 - 2430363 2430363
RECOMBINANT HUMAN TRANSFORMING GROWTH FACTOR-β2 2474855
RECOMBINANT HUMAN TRANSFORMING GROWTH FACTOR-β2 3131192
RECOMBINANT HUMAN TRANSFORMING GROWTH FACTOR-β2 2726168
RECOMBINANT HUMAN TRANSFORMING GROWTH FACTOR-β2 2976534
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Data Sheet

Title
Reprogramming Cell Fate and Function Novel Strategies for iPSC Generation, Characterization, and Differentiation

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Categories

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Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors