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596200 Thioflavin T - CAS 2390-54-7 - Calbiochem

A cell-permeable benzothiazole dye that exhibits enhanced fluorescence upon binding to amyloid fibrils.

Thioflavin T - CAS 2390-54-7 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: ThT, Thioflavine T, Basic Yellow 1

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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
2390-54-7C₁₇H₁₉ClN₂S

Products

Catalogue NumberPackaging Qty/Pack
596200-500MG Plastic ampoule 500 mg
Description
OverviewA cell-permeable benzothiazole dye that exhibits enhanced fluorescence upon binding to amyloid fibrils. Useful in monitoring stacked β sheet aggregates.
Catalogue Number596200
Brand Family Calbiochem®
SynonymsThT, Thioflavine T, Basic Yellow 1
References
ReferencesTjernberg, L.O., et al. 1999. J. Biol. Chem. 274, 12619.
Naiki, H. and Nakakuki, K. 1996. Lab. Invest. 74, 374.
LeVine, H. 1993. Protein Sci. 2, 404.
Product Information
CAS number2390-54-7
ATP CompetitiveN
FormYellow solid
Hill FormulaC₁₇H₁₉ClN₂S
Chemical formulaC₁₇H₁₉ClN₂S
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetExhibits enhanced fluorescence upon binding to amyloid fibrils
Physicochemical Information
Cell permeableY
Emission max.
Excitation max.
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +15°C to +30°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
596200-500MG 04055977189131

Documentation

Thioflavin T - CAS 2390-54-7 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Thioflavin T - CAS 2390-54-7 - Calbiochem Certificates of Analysis

TitleLot Number
596200

References

Reference overview
Tjernberg, L.O., et al. 1999. J. Biol. Chem. 274, 12619.
Naiki, H. and Nakakuki, K. 1996. Lab. Invest. 74, 374.
LeVine, H. 1993. Protein Sci. 2, 404.

Brochure

Title
Alzheimer's Disease Brochure & Technical Guide
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision12-September-2008 RFH
SynonymsThT, Thioflavine T, Basic Yellow 1
DescriptionA cell-permeable benzothiazole dye that exhibits enhanced fluorescence upon binding to amyloid fibrils. Useful in monitoring stacked β sheet aggregates. Associates with aggregated fibrils of synthetic β/A4-derived peptides β(1-28) and β(1-40), resulting in a shift in the excitation maximum and an enhanced emission. Excitation max.: ~385 nm (free); ~437 nm (bound); emission max.: ~445 nm (free); ~485 nm (bound).
FormYellow solid
Intert gas (Yes/No) Packaged under inert gas
CAS number2390-54-7
Chemical formulaC₁₇H₁₉ClN₂S
Structure formulaStructure formula
SolubilityH₂O (5 mg/ml)
Storage Protect from light
+15°C to +30°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Standard Handling
ReferencesTjernberg, L.O., et al. 1999. J. Biol. Chem. 274, 12619.
Naiki, H. and Nakakuki, K. 1996. Lab. Invest. 74, 374.
LeVine, H. 1993. Protein Sci. 2, 404.