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574105 Sulindac Sulfone

574105
  
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
59864-04-9C₂₀H₁₇FO₄S
Description
Overview

This product has been discontinued.





A cell-permeable sulfone metabolite of Sulindac (Cat. No. 574100) that has anticancer properties but lacks cyclooxygenase (COX) inhibitory activity. Also inhibits cell growth and induces apoptosis.
Catalogue Number574105
Brand Family Calbiochem®
Synonyms(Z)-5-Fluoro-2-methyl-1[p-(methylsulfonyl)benzylidene]indene-3-acetic Acid, Exisulind, FGN-1
References
ReferencesGoluboff, E.T., et al. 1999. Urology 63, 440.
Lim, J.T., et al. 1999. Biochem. Pharmacol. 58, 1097.
Piazza, G.A., et al. 1995. Cancer Res. 55, 3110.
Product Information
CAS number59864-04-9
FormYellow solid
Hill FormulaC₂₀H₁₇FO₄S
Chemical formulaC₂₀H₁₇FO₄S
Structure formula ImageStructure formula Image
Applications
Biological Information
Primary Targetcell growth
Purity≥98% by TLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +15°C to +30°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
574105 0

Documentation

Sulindac Sulfone Certificates of Analysis

TitleLot Number
574105

References

Reference overview
Goluboff, E.T., et al. 1999. Urology 63, 440.
Lim, J.T., et al. 1999. Biochem. Pharmacol. 58, 1097.
Piazza, G.A., et al. 1995. Cancer Res. 55, 3110.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision13-September-2007 JSW
Synonyms(Z)-5-Fluoro-2-methyl-1[p-(methylsulfonyl)benzylidene]indene-3-acetic Acid, Exisulind, FGN-1
DescriptionA cell-permeable sulfone metabolite of Sulindac (Cat. No. 574100) that has anticancer properties but lacks cyclooxygenase (COX) inhibitory activity. Also inhibits cell growth and induces apoptosis.
FormYellow solid
CAS number59864-04-9
Chemical formulaC₂₀H₁₇FO₄S
Structure formulaStructure formula
Purity≥98% by TLC
SolubilityDMSO (25 mg/ml) or Ethanol (3 mg/ml)
Storage +15°C to +30°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesGoluboff, E.T., et al. 1999. Urology 63, 440.
Lim, J.T., et al. 1999. Biochem. Pharmacol. 58, 1097.
Piazza, G.A., et al. 1995. Cancer Res. 55, 3110.