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537009 Progranulin, CF, Mouse, Recombinant

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537009
  
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Overview

Key Spec Table

Purity
≥90% by SDS-PAGE
Description
Overview

This product has been discontinued.



Recombinant, mouse progranulin, consisting of amino acids 18-589, fused at the C-terminus to a His•Tag® sequence, and expressed in NS0-derived mouse myeloma cells. Progranulin is an ubiquitously expressed, secreted glycoprotein that is involved in regulation of cell proliferation.

Catalogue Number537009
Brand Family Calbiochem®
SynonymsPC cell-derived growth factor (PCDGF)
References
ReferencesLiu, Y. et al. 2007. BMC Cancer 7, 22.
Xu, K. et al. 2007. J. Biol. Chem. 282, 11347.
Barreda, D.R. et al. 2004. Dev. Comp. Immunol. 28, 727.
Davidson, B. et al. 2004. Cancer 100, 2139.
Sun, X. et al. 2004. Am. J. Respir. Cell Mol. Biol. 30, 510.
Gonzalez, E.M. et al. 2003. J. Biol. Chem. 278, 38113.
He, Z. et al. 2003. Nat. Med. 9, 225.
He, Z. and Bateman, A. 2003. J. Mol. Med. 81, 600.
Jones, M.B. et al. 2003. Gynecol. Oncol. 88, S136.
Wang, W. et al. 2003. Clin. Cancer Res. 9, 2221.
Suzuki, M. and Nishiahara, M. 2002. Mol. Genet. Metab. 75, 31.
Zhu, J. et al. 2002. Cell 111, 867.
Lu, R. and Serrero, G. 2000. Proc. Natl. Acad. Sci. U.S.A. 97, 3993.
Justen, H.P. et al. 2000. Mol. Cell Biol. Res. Commun. 3, 165.
Zanocco Marani, T. et al. 1999. Cancer Res. 59, 5331.
Zhang, H. and G. Serrero 1998. Proc. Natl. Acad. Sci. U.S.A. 95, 14202.
Zhou, J. et al. 1993. J. Biol. Chem. 268, 10863.
Plowman, G.D. et al. 1992. J. Biol. Chem. 267, 13073.
Bateman, A. et al. 1990. Biochem. Biophys. Res. Commun. 173, 1161.
Product Information
FormLyophilized
FormulationLyophilized from 0.2 µm filtered PBS.
Quality LevelMQ100
Biological Information
Biological activitySignificantly enhances neurite outgrowth of E18 rat embryonic cortical neurons using 4-16 µg/ml progranulin immobilized on nitrocelluose-coated microplates.
Purity≥90% by SDS-PAGE
Physicochemical Information
ContaminantsEndotoxin: ≤1.0 EU/µg protein
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
Global Trade Item Number
Catalogue Number GTIN
537009 0