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14-642M PTPMEG-1 Protein, 250 µg

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14-642M
250 µg  Also available in 10 μg size (cat#14-642) and in bulk (cat#14-642-K).
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Overview

Replacement Information
Description
Catalogue Number14-642M
Brand Family Upstate
Trade Name
  • Upstate
DescriptionPTPMEG-1 Protein, 250 µg
OverviewN-Terminal GST-tagged, recombinant, human PTPMEG-1, amino acids 423-end
References
Product Information
Quality LevelMQ300
Applications
ApplicationN-terminal GST-tagged, recombinant, human PTPMEG-1, amino acids 423-end, for use in Phosphatase Assays.
Key Applications
  • Phosphatase Assay
Biological Information
Sourcerecombinant human PTPMEG-1, amino acids 423-end
Entrez Gene Number
Entrez Gene SummaryThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signalling downstream of the glutamate receptors through tyrosine dephosphorylation.
Gene Symbol
  • PTPN4
  • MEG
  • PTPMEG1
  • PTPMEG
  • PTPase-MEG1
Protein TargetPTPMEG-1
Purification MethodGlutathione agarose affinity chromatography
Target Sub-FamilyTyr phosphatase
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P29074 # May act at junctions between the membrane and the cytoskeleton.
SIZE: 926 amino acids; 105911 Da
SIMILARITY: SwissProt: P29074 ## Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily. & Contains 1 FERM domain. & Contains 1 PDZ (DHR) domain. & Contains 1 tyrosine-protein phosphatase domain.
Molecular Weight83.1kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated in a PTPMEG-1 Phosphatase Assay
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions6 months at -70°C
Packaging Information
Material Size250 µg
Material PackageAlso available in 10 μg size (cat#14-642) and in bulk (cat#14-642-K).
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
14-642M 04053252924507

Documentation

Related Products & Applications

Alternative Packsize

Catalogue Number Description
14-642 PTPMEG-1 Protein, 10 µg

Product Families

Categories

Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Phosphatases
Life Science Research > Proteins and Enzymes > Purified Phosphatases