Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

459618 Okadaic Acid, Potassium Salt - CAS 155751-72-7 - Calbiochem

Okadaic Acid, Potassium Salt, CAS 155751-72-7, is a water-soluble analog of Okadaic Acid (Cat. No. 495604). A potent inhibitor of protein phosphatase 1 (IC50 = 10-15 nM) and 2A (IC50 = 0.1 nM).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Primary Target: PP1, PP2
View Products on Sigmaaldrich.com
459618
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
155751-72-7C₄₄H₆₇ O₁₃ · K

Products

Catalogue NumberPackaging Qty/Pack
459618-50UG Alu drum 50 μg
Description
OverviewWater-soluble analog of Okadaic Acid (Cat. No. 495604). Inhibits protein phosphatases 1 and 2A.
Catalogue Number459618
Brand Family Calbiochem®
References
ReferencesGjertsen, B.T., et al. 1994. J. Cell Sci. 107, 3363.
Kiguchi, K., et al. 1994. Cell Growth Differ. 5, 995.
Ohaka, Y., et al. 1993. Biochem. Biophys. Res. Commun. 197, 916.
Gopalakrishna, R., et al. 1992. Biochem. Biophys. Res. Commun. 189, 950.
Kreienbuhl, P., et al. 1992. Blood 80, 2911.
Nomura, M., et al. 1992. Biochemistry 31, 11915.
Song, Q., et al. 1992. J. Cell Physiol. 153, 550.
Tada, Y., et al. 1992. Immunopharmacol. 24, 17.
Product Information
CAS number155751-72-7
ATP CompetitiveN
FormClear colorless solid film
Hill FormulaC₄₄H₆₇ O₁₃ · K
Chemical formulaC₄₄H₆₇ O₁₃ · K
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
ApplicationOkadaic Acid, Potassium Salt, CAS 155751-72-7, is a water-soluble analog of Okadaic Acid (Cat. No. 495604). A potent inhibitor of protein phosphatase 1 (IC50 = 10-15 nM) and 2A (IC50 = 0.1 nM).
Biological Information
Primary TargetPP1, PP2
Primary Target IC<sub>50</sub>10-15 nM, 0.1 nM, against protein phosphatase 1 and protein phosphatase 2A, respectively
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 23/24/25-38

Toxic by inhalation, in contact with skin and if swallowed.
Irritating to skin.
S PhraseS: 22-26-36/37/39-45

Do not breathe dust.
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Toxic
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
459618-50UG 04055977185294

Documentation

Okadaic Acid, Potassium Salt - CAS 155751-72-7 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Okadaic Acid, Potassium Salt - CAS 155751-72-7 - Calbiochem Certificates of Analysis

TitleLot Number
459618

References

Reference overview
Gjertsen, B.T., et al. 1994. J. Cell Sci. 107, 3363.
Kiguchi, K., et al. 1994. Cell Growth Differ. 5, 995.
Ohaka, Y., et al. 1993. Biochem. Biophys. Res. Commun. 197, 916.
Gopalakrishna, R., et al. 1992. Biochem. Biophys. Res. Commun. 189, 950.
Kreienbuhl, P., et al. 1992. Blood 80, 2911.
Nomura, M., et al. 1992. Biochemistry 31, 11915.
Song, Q., et al. 1992. J. Cell Physiol. 153, 550.
Tada, Y., et al. 1992. Immunopharmacol. 24, 17.

Brochure

Title
Protein Phosphatases Technical Bulletin
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision28-July-2020 JSW
DescriptionWater-soluble analog of Okadaic Acid (Cat. No. 495604). Inhibits protein phosphatases 1 and 2A.
FormClear colorless solid film
CAS number155751-72-7
Chemical formulaC₄₄H₆₇ O₁₃ · K
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityDMSO (20 mg/ml), Ethanol (20 mg/ml), or H₂O (1 mg/ml)
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Toxicity Toxic
ReferencesGjertsen, B.T., et al. 1994. J. Cell Sci. 107, 3363.
Kiguchi, K., et al. 1994. Cell Growth Differ. 5, 995.
Ohaka, Y., et al. 1993. Biochem. Biophys. Res. Commun. 197, 916.
Gopalakrishna, R., et al. 1992. Biochem. Biophys. Res. Commun. 189, 950.
Kreienbuhl, P., et al. 1992. Blood 80, 2911.
Nomura, M., et al. 1992. Biochemistry 31, 11915.
Song, Q., et al. 1992. J. Cell Physiol. 153, 550.
Tada, Y., et al. 1992. Immunopharmacol. 24, 17.