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487952 NOC-7 - CAS 146724-84-7 - Calbiochem

A nitric oxide (NO) donor similar to NOC-5 but with a much shorter half-life of NO release.

NOC-7 - CAS 146724-84-7 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 3-(2-Hydroxy-1-methyl-2-nitrosohydrazino)-N-methyl-1-propanamine

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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
146724-84-7C₅H₁₄N₄O₂
Description
OverviewA nitric oxide (NO) donor similar to NOC-5 (Cat. No. 487950) but with a much shorter half-life of NO release. Half-life (t½) in PBS, pH 7.4 is 10 minutes at 22°C. Useful as a short-acting nitrovasodilator. Relatively stable in alkaline solution (pH ≥10.0).
Catalogue Number487952
Brand Family Calbiochem®
Synonyms3-(2-Hydroxy-1-methyl-2-nitrosohydrazino)-N-methyl-1-propanamine
References
ReferencesZhang, P., et al. 1996. Circulation 94, 2235.
Hrabie, J.A., et al. 1993. J. Org. Chem. 58, 1472.
Product Information
CAS number146724-84-7
ATP CompetitiveN
FormWhite solid
Hill FormulaC₅H₁₄N₄O₂
Chemical formulaC₅H₁₄N₄O₂
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetA nitric oxide (NO) donor
Purity≥90% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 36/37/38

Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage -20°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution in alkaline solution, aliquot and freeze (-20°C). Unstable in aqueous solutions; reconstitute in H₂O jut prior to use. Alkaline stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
487952 0

Documentation

NOC-7 - CAS 146724-84-7 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

NOC-7 - CAS 146724-84-7 - Calbiochem Certificates of Analysis

TitleLot Number
487952

References

Reference overview
Zhang, P., et al. 1996. Circulation 94, 2235.
Hrabie, J.A., et al. 1993. J. Org. Chem. 58, 1472.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision13-August-2008 RFH
Synonyms3-(2-Hydroxy-1-methyl-2-nitrosohydrazino)-N-methyl-1-propanamine
DescriptionA nitric oxide (NO) donor similar to NOC-5 (Cat. No. 487950) but with a much shorter half-life of NO release. Useful as a short-acting nitrovasodilator. Half-life (t½) of NO release = 10 min (PBS, pH 7.4, 22°C).
FormWhite solid
CAS number146724-84-7
Chemical formulaC₅H₁₄N₄O₂
Structure formulaStructure formula
Purity≥90% by HPLC
SolubilityH₂O or 0.1 N NaOH (≥ pH 10)
Storage Protect from light
-20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution in alkaline solution, aliquot and freeze (-20°C). Unstable in aqueous solutions; reconstitute in H₂O jut prior to use. Alkaline stock solutions are stable for up to 3 months at -20°C.
Toxicity Irritant
ReferencesZhang, P., et al. 1996. Circulation 94, 2235.
Hrabie, J.A., et al. 1993. J. Org. Chem. 58, 1472.