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509884 Myristoylated-FEEERA, mP6 - Calbiochem

A cell-permeable myristoylated hexapeptide that selectively inhibits integrin outside-in signaling without affecting inside-out signaling. Blocks the interaction of Gα3 and integrin β3 subunit.

Myristoylated-FEEERA, mP6 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Integrin Signaling Inhibitor I, mP6

Primary Target: platelet integrin →IIb→3
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₄₇H₇₅N₉O₁₄

Products

Catalogue NumberPackaging Qty/Pack
5.09884.0001 Glass bottle 10 mg
Description
OverviewA cell-permeable myristoylated hexapeptide derived from EXE-motif-containing integrin β3 subunit that selectively inhibits integrin outside-in signaling without affecting inside-out signaling . Shown to specifically block the interaction of Gα3 and integrin β3 subunit resulting in the inhibition of Gα13-dependent early phase outside-in signaling. Selectively inhibits thrombosis without affecting haemostasis.

Please note that the molecular weight for this compound is batch-specific due to variable water content.
Catalogue Number509884
Brand Family Calbiochem®
SynonymsIntegrin Signaling Inhibitor I, mP6
References
ReferencesShen, B., et al. 2013. Nature 503, 131.
Product Information
FormWhite powder
Hill FormulaC₄₇H₇₅N₉O₁₄
Chemical formulaC₄₇H₇₅N₉O₁₄
Hygroscopic Hygroscopic
ReversibleY
Quality LevelMQ100
Applications
Biological Information
Primary Targetplatelet integrin →IIb→3
Purity≥98% by HPLC
Physicochemical Information
Cell permeableY
Peptide SequenceFEEERA
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage ≤ -70°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-207deg;C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
5.09884.0001 04055977241136

Documentation

Myristoylated-FEEERA, mP6 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

References

Reference overview
Shen, B., et al. 2013. Nature 503, 131.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision09-May-2014 JSW
SynonymsIntegrin Signaling Inhibitor I, mP6
DescriptionA cell-permeable myristoylated hexapeptide derived from EXE-motif-containing integrin β3 subunit that selectively inhibits integrin outside-in signaling without affecting inside-out signaling . Shown to specifically block the interaction of Gα3 and integrin β3 subunit resulting in the inhibition of Gα13-dependent early phase outside-in signaling. Selectively inhibits thrombosis without affecting haemostasis.
FormWhite powder
Intert gas (Yes/No) Packaged under inert gas
Chemical formulaC₄₇H₇₅N₉O₁₄
Peptide SequenceFEEERA
Purity≥98% by HPLC
SolubilityDMSO (100 mg/ml)
Storage Protect from light
≤ -70°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-207deg;C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesShen, B., et al. 2013. Nature 503, 131.