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444224 MMP-2/MMP-9 Substrate II - Calbiochem

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Overview

Description
OverviewAn exceptional thiopeptide that is used as a substrate for the rapid, sensitive, and continuous spectrophotometric assay of Type IV collagenases, MMP-2 (gelatinase A), and MMP-9 (gelatinase B). Also acts as a substrate for vertebrate collagenase. Cleavage is monitored at 324 nm.
Catalogue Number444224
Brand Family Calbiochem®
SynonymsAc-Pro-Leu-Gly-(2-mercapto-4-methylpentanoyl)-Leu-Gly-OEt, Gelatinase A/Gelatinase B Substrate II
References
ReferencesWeingarten, H., et al. 1985. Anal. Biochem. 147, 437.
Weingarten, H., et al. 1985. Biochemistry 24, 6730.
Product Information
ATP CompetitiveN
FormWhite solid
Hill FormulaC₃₁H₅₃N₅O₈S
Chemical formulaC₃₁H₅₃N₅O₈S
ReversibleN
Quality LevelMQ100
Biological Information
Primary TargetSubstrate for the rapid, sensitive, and continuous spectrophotometric assay of Type IV collagenases, MMP-2 (gelatinase A), and MMP-9 (gelatinase B).
Purity≥97% by HPLC
Physicochemical Information
Cell permeableN
Peptide SequenceAc-Pro-Leu-Gly-SCH[CH₂CH(CH₃)₂]-CO-Leu-Gly-OC₂H₅
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsUnstable in solution; reconstitute just prior to use.
Global Trade Item Number
Catalogue Number GTIN
444224 0