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509705 L-Serine-O-phosphate - CAS 407-41-0 - Calbiochem

A potent agonist for group III mGlu receptor subtype 4, 6, and 8.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: L-2-Amino-3-hydroxypropanoic acid 3-phosphate, L-SOP, L-Serine O-phosphate

Primary Target: mGlu₄, mGlu₆, mGlu₈
509705
  
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
407-41-0C₃H₈NO₆P
Description
Overview

This product has been discontinued.



A potent agonist for group III mGlu receptor subtype 4, 6, and 8 (EC50 = 1-4, 3, and 2 µM for mGlu4, mGlu6, mGlu8, respectively); but not for subtype 7 (EC50 = 160-1200 µM). Inhibits proliferation and enhances neuronal differentiation in progenitor cells. Widely used to study presynaptic inhibitory modulation of the excitatory glutamatergic transmission at retina and central nervous systems.

Please note that the molecular weight for this compound is batch-specific due to variable water content.
Catalogue Number509705
Brand Family Calbiochem®
SynonymsL-2-Amino-3-hydroxypropanoic acid 3-phosphate, L-SOP, L-Serine O-phosphate
References
ReferencesEriksen, L., et al. 1995. Br. J. Pharmacol. 116, 3279.
Thoreson, W., et al. 1995. Brain Res. 676, 93.
Bruno, V., et al. 1996. Eur. J. Pharmacol. 310, 61.
Saxe, J., et al. 2007. Chem. Biol. 14, 1019.
Nakajima, Y., 1993. J. Biol. Chem. 268, 11868.
Product Information
CAS number407-41-0
FormOff-white powder
Hill FormulaC₃H₈NO₆P
Chemical formulaC₃H₈NO₆P
Quality LevelMQ100
Applications
Biological Information
Primary TargetmGlu₄, mGlu₆, mGlu₈
Purity≥98% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +15°C to +30°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
509705 0

Documentation

L-Serine-O-phosphate - CAS 407-41-0 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

References

Reference overview
Eriksen, L., et al. 1995. Br. J. Pharmacol. 116, 3279.
Thoreson, W., et al. 1995. Brain Res. 676, 93.
Bruno, V., et al. 1996. Eur. J. Pharmacol. 310, 61.
Saxe, J., et al. 2007. Chem. Biol. 14, 1019.
Nakajima, Y., 1993. J. Biol. Chem. 268, 11868.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision28-April-2014 JSW
SynonymsL-2-Amino-3-hydroxypropanoic acid 3-phosphate, L-SOP, L-Serine O-phosphate
DescriptionA potent agonist for group III mGlu receptor subtype 4, 6, and 8 (EC50 = 1-4, 3, and 2 µM for mGlu4, mGlu6, mGlu8, respectively); but not for subtype 7 (EC50 = 160-1200 µM). Inhibits proliferation and enhances neuronal differentiation in progenitor cells. Widely used to study presynaptic inhibitory modulation of the excitatory glutamatergic transmission at retina and central nervous systems.
FormOff-white powder
Intert gas (Yes/No) Packaged under inert gas
CAS number407-41-0
Chemical formulaC₃H₈NO₆P
Purity≥98% by HPLC
SolubilityH₂O (50 mg/ml)
Storage Protect from light
+15°C to +30°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesEriksen, L., et al. 1995. Br. J. Pharmacol. 116, 3279.
Thoreson, W., et al. 1995. Brain Res. 676, 93.
Bruno, V., et al. 1996. Eur. J. Pharmacol. 310, 61.
Saxe, J., et al. 2007. Chem. Biol. 14, 1019.
Nakajima, Y., 1993. J. Biol. Chem. 268, 11868.