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420123 JNK Inhibitor II, Negative Control - CAS 54642-23-8 - Calbiochem

Overview

Key Spec Table

CAS #Empirical Formula
54642-23-8C₁₅H₁₀N₂O

Products

Catalogue NumberPackaging Qty/Pack
420123-1MG Plastic ampoule 1 mg
Description
OverviewA useful negative control for JNK Inhibitor II (SP600125, Cat. No. 420119). Inhibits JNK2 and JNK3 only at much higher concentrations (IC50 = 18 µM and 24 µM, respectively) compared to SP600125 (IC50 = 40 nM and 90 nM, respectively).
Catalogue Number420123
Brand Family Calbiochem®
SynonymsN¹-Methyl-1,9-pyrazoloanthrone
References
ReferencesShin, M., and Boyd, Y.D. 2002. Biochim. Biophys. Acta 1589, 311.
Bennett, B.L., et al. 2001. Proc. Natl. Acad. Sci. USA 98, 13681.
Product Information
CAS number54642-23-8
ATP CompetitiveY
FormYellow solid
Hill FormulaC₁₅H₁₀N₂O
Chemical formulaC₁₅H₁₀N₂O
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Primary TargetA useful negative control for JNK Inhibitor II (SP600125, Cat. No. 420119)
Primary Target IC<sub>50</sub>18 µM and 24 µM against JNK2 and JNK3, respectively
Purity≥97% by HPLC
Physicochemical Information
Cell permeableY
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Global Trade Item Number
Catalogue Number GTIN
420123-1MG 04055977188035