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474791 InSolution™ MG-132 - CAS 133407-82-6 - Calbiochem

Overview

Key Spec Table

CAS #Empirical Formula
133407-82-6C₂₆H₄₁N₃O₅

Products

Catalogue NumberPackaging Qty/Pack
474791-1MG Plastic ampoule 1 mg
474791-5MG Plastic ampoule 5 mg
Description
Catalogue Number474791
Brand Family Calbiochem®
SynonymsCarbobenzoxy-L-leucyl-L-leucyl-L-leucinal, Z-LLL-CHO, Proteasome Inhibitor XI
References
ReferencesMeriin, A.B., et al. 1998. J. Biol. Chem. 273, 6373.
Adams, J., and Stein, R. 1996. Ann. Rep. Med. Chem. 31, 279.
Lee, D.H., and Goldberg, A.L. 1996. J. Biol. Chem. 271, 27280.
Wiertz, E.J.H.J., et al. 1996. Cell 84, 769.
Read, M.A., et al. 1995. Immunity 2, 493.
Rock, K.L., et al. 1994. Cell 78, 761.
Product Information
CAS number133407-82-6
ATP CompetitiveN
FormLiquid
FormulationA 10 mM (1 mg/210 µl) or (5mg/1050 µl) solution of MG-132 (Cat. No. 474790) in DMSO.
Hill FormulaC₂₆H₄₁N₃O₅
Chemical formulaC₂₆H₄₁N₃O₅
ReversibleY
Quality LevelMQ100
Biological Information
Primary Targetproteasome
Primary Target IC<sub>50</sub>3 µM in inhibiting NF-κB activation
Primary Target K<sub>i</sub>4 nM as proteasome inhibitor
Purity≥98% by HPLC
Physicochemical Information
Cell permeableY
Safety Information
R PhraseR: 36/38

Irritating to eyes and skin.
S PhraseS: 26-36-45

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Irritant
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Packaging Information
Packaged under inert gas Packaged under inert gas
Global Trade Item Number
Catalogue Number GTIN
474791-1MG 04055977185515
474791-5MG 04055977185522