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218840 InSolution™ Caspase-8 Inhibitor II - Calbiochem

Overview

Replacement Information

Key Spec Table

Empirical Formula
C₃₀H₄₃FN₄O₁₁

Products

Catalogue NumberPackaging Qty/Pack
218840-250UG Glass bottle 250 μg
Description
Catalogue Number218840
Brand Family Calbiochem®
SynonymsGranzyme B Inhibitor III; Z-IE(OMe)TD(OMe)-FMK
References
ReferencesMartin, D.A., et al. 1998. J. Biol. Chem. 273, 4345.
Sweeney, E.A., et al. 1998. FEBS Lett. 425, 61.
Product Information
ATP CompetitiveN
FormLiquid
FormulationA 5 mM (250 µg/76 µl) solution of Z-IETD-FMK (Cat. No. 218759) in DMSO.
Hill FormulaC₃₀H₄₃FN₄O₁₁
Chemical formulaC₃₀H₄₃FN₄O₁₁
Hygroscopic Hygroscopic
ReversibleN
Quality LevelMQ100
Applications
Biological Information
Primary Targetcaspase-8
Purity≥98% by HPLC
Physicochemical Information
Cell permeableY
Peptide SequenceZ-Ile-Glu(OMe)-Thr-Asp(OMe)-CH₂F*
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 36/38

Irritating to eyes and skin.
S PhraseS: 26

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Irritant
Storage -20°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
218840-250UG 04055977218923

Documentation

InSolution™ Caspase-8 Inhibitor II - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

InSolution™ Caspase-8 Inhibitor II - Calbiochem Certificates of Analysis

TitleLot Number
218840

References

Reference overview
Martin, D.A., et al. 1998. J. Biol. Chem. 273, 4345.
Sweeney, E.A., et al. 1998. FEBS Lett. 425, 61.

Brochure

Title
Caspases and other Apoptosis Related Tools Brochure
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision14-November-2023 JSW
SynonymsGranzyme B Inhibitor III; Z-IE(OMe)TD(OMe)-FMK
DescriptionA 5 mM (250 µg/76 µl) solution of Z-IETD-FMK (Cat. No. 218759) in DMSO. Z-IETD-FMK is a potent, cell-permeable, and irreversible inhibitor of caspase-8 (MACH, FLICE, Mch5). Also inhibits granzyme B.
FormLiquid
FormulationA 5 mM (250 µg/76 µl) solution of Z-IETD-FMK (Cat. No. 218759) in DMSO.
Intert gas (Yes/No) Packaged under inert gas
Chemical formulaC₃₀H₄₃FN₄O₁₁
Peptide SequenceZ-Ile-Glu(OMe)-Thr-Asp(OMe)-CH₂F*
Purity≥98% by HPLC
Storage Protect from light
-20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Toxicity Irritant
ReferencesMartin, D.A., et al. 1998. J. Biol. Chem. 273, 4345.
Sweeney, E.A., et al. 1998. FEBS Lett. 425, 61.