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23-052M Hsp70 Protein, 250 µg

Full length, recombinant human Hsp70. N-terminal c-Myc, 6His-tagged. For use in Enzyme Assays. Functions as a substrate in ubiquitination assays.

Hsp70 Protein, 250 µg MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Key Applications: Enzyme Assays
23-052M
250 µg  
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

Key ApplicationsSpeciesCascade Component
Enzyme AssaysHuman Substrate
Description
Catalogue Number23-052M
Brand Family Upstate
Trade Name
  • Upstate
DescriptionHsp70 Protein, 250 µg
Alternate Names
  • Heat shock 70 kDa protein 1A/1B
  • HSPA1A
  • HSPA1B
Background InformationHsp70 proteins are central components of the cellular network of molecular chaperones. They assist in a wide range of processes, including the folding and assembly of newly synthesized proteins, refolding of misfolded and aggregated proteins, membrane translocation of organellar and secretory proteins, and control of the activity of regulatory proteins. The cellular levels of Hsp70 are thought to be at least partially regulated by the E3 ubiquitin ligase CHIP, which also targets a broad range of Hsp70 chaperone substrates for proteosomal degradation. Consistent with its diverse activities, genetic and biochemical studies have implicated Hsp70 in a range of diseases including cancer, neurodegeneration, allograft rejection and infection.
References
Product Information
Quality LevelMQ300
Applications
ApplicationFull length, recombinant human Hsp70. N-terminal c-Myc, 6His-tagged. For use in Enzyme Assays. Functions as a substrate in ubiquitination assays.
Key Applications
  • Enzyme Assays
Biological Information
Cascade ComponentSubstrate
Entrez Gene Number
Purification MethodPurified using immobilized metal affinity chromatography.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Packaging Information
Material Size250 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
23-052M 04053252649912

Related Products & Applications

Alternative Packsize

Catalogue Number Description
23-052 Hsp70 Protein, 10 µg

Product Families

Ubiquitin Proteasome System: Enzymes and Substrates

Millipore has removed the complexity of Ubiquitination by providing functionally validated enzymes and substrates, making the pathway readily accessible for research and drug discovery.
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Categories

Life Science Research > Drug Discovery and Development > Ubiquitin and Proteasome Screening > Ubiquitination Substrates
Life Science Research > Proteins and Enzymes > Substrate & Control Proteins > Ubiquitination Substrates