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373386 Hh Signaling Pathway Modulators

373386
  
Purchase on Sigma-Aldrich

Overview

Description
Overview

This product has been discontinued.



A panel containing 14 potent, selective and cell-permeable antagonists, inhibitors and agonists that are useful for the study of the Hh (Hedgehog) signaling pathway: 5 mg of βARK1 Inhibitor (Cat. No. 182200), 100 µg of Cyclopamine-KAAD (Cat. No. 239804), 25 mg of Fluvastatin, Sodium Salt (Cat. No. 344095), 1 mg of GSK-3 Inhibitor IX; BIO (Cat. No. 361550), 1 mg of H-89, Dihydrochloride (Cat. No. 371963), 10 mg of Hh Signaling Antagonist XIV; SANT-2 (Cat. No. 373273), 10 mg of Hh Signaling Antagonist XII; HPI-1 (Cat. No. 373275), 10 mg of Hh Signaling Antagonist XIII; HPI-3 (Cat. No. 373276), 5 mg of Hh/Gli Antagonist; GANT61 (Cat. No. 373401), 5 mg of Hh Signaling Antagonist VII; JK184 (Cat. No. 373385), 5 mg of IC261 (Cat. No. 400090), 5 mg of MG-132 (Cat. No. 474790), 5 mg of Purmorphamine (Cat. No. 540220) and 1 mg of Smoothened Agonist; SAG (Cat. No. 566660). Also provided with 15 ml of anhydrous DMSO (Cat. No. KP31817). Supplied with a data sheet.

Catalogue Number373386
Brand Family Calbiochem®
Application Data
References
ReferencesPeukert, S. and Miller-Moslin, K., 2010. Chem. Med. Chem. 6, 500.
Tremblay, M.R., et al. 2010. Curr. Opin. Chem. Biol. 14, 428.
Scales, S.J. and de Sauvage, F. J., 2009. Trends. Pharmacol. Sci. 30, 303.
Jiang, J. and Hui, C.C., 2008. Dev. Cell 15, 801.
Lum, L. and Beachy, P.A, 2004. Science 304, 1755
Ingham, P.W. and McMohan, A.P., 2001. Genes Dev. 15, 3059.
Product Information
FormSolid
Hygroscopic Hygroscopic
Quality LevelMQ100
Safety Information
R PhraseR: 20/21/22-36/38

Harmful by inhalation, in contact with skin and if swallowed.
Irritating to eyes and skin.
S PhraseS: 22-24/25-36/37/39-45

Do not breathe dust.
Avoid contact with skin and eyes.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Storage and Shipping Information
Ship Code Shipped with Blue Ice or with Dry Ice
Toxicity Harmful
Storage -20°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C).
Packaging Information
Packaged under inert gas Packaged under inert gas
Global Trade Item Number
Catalogue Number GTIN
373386 0