534329 Sigma-AldrichH₂S Fluorescent Probe, P3 - Calbiochem
A cell-permeable, specific, sensitive, fast-responsive fluorescent turn-on H₂S probe. Monitors endogenous [H₂S] in live cells by two-photon imaging.
More>> A cell-permeable, specific, sensitive, fast-responsive fluorescent turn-on H₂S probe. Monitors endogenous [H₂S] in live cells by two-photon imaging. Less<<Synonyms: (E)-2-(3-(6-(2-Hydroxyethylamino)naphthalen-2-yl)-3-oxoprop-1-enyl)-3,5-dimethoxybenzaldehyde, Hydrogen Sulfide Fluorescent Probe, P3, Probe P3
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Overview
Replacement Information |
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Key Spec Table
Empirical Formula |
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C₂₄H₂₃NO₅ |
Products
Catalogue Number | Packaging | Qty/Pack | |
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5.34329.0001 | Glass bottle | 5 mg |
Description | |
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Overview | A cell-permeable, non-toxic, non-fluorescent naphthalenyl-dimethoxybenzaldehyde enone compound that acts as a highly specific, sensitive, fast-responsive H2S fluoroprobe (signal saturation at ≤ 5 min with a detection limit of 50 nM). Dose-dependently detects hydrogen sulfide levels under physiological conditions and readily fluoresces. Displays little to no reactivity towards GSH, Cys, H2O2, citrate and iodide (Hepes pH 7.4, containing 10% FBS). Also shown to be useful as a two-photon probe for imaging endogeneous H2S levels in HeLa cells. A thiol specific fluorescent probe is also available (Cat. No. 595504). Please note that the molecular weight for this compound is batch-specific due to variable water content. Please refer to the vial label or the certificate of analysis for the batch-specific molecular weight. The molecular weight provided represents the baseline molecular weight without water. |
Catalogue Number | 534329 |
Brand Family | Calbiochem® |
Synonyms | (E)-2-(3-(6-(2-Hydroxyethylamino)naphthalen-2-yl)-3-oxoprop-1-enyl)-3,5-dimethoxybenzaldehyde, Hydrogen Sulfide Fluorescent Probe, P3, Probe P3 |
References | |
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References | Singha, S., et al. 2015. Anal. Chem. 87, 1188. |
Product Information | |
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Form | Orange solid |
Hill Formula | C₂₄H₂₃NO₅ |
Chemical formula | C₂₄H₂₃NO₅ |
Reversible | N |
Quality Level | MQ100 |
Applications |
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Biological Information | |
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Primary Target | hydrogen sulfide |
Purity | ≥98% by HPLC |
Physicochemical Information | |
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Cell permeable | Y |
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Dimensions |
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Materials Information |
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Toxicological Information |
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Safety Information according to GHS |
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Safety Information |
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Product Usage Statements |
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Packaging Information | |
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Packaged under inert gas | Packaged under inert gas |
Transport Information |
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Supplemental Information |
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Specifications |
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Global Trade Item Number | |
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Catalogue Number | GTIN |
5.34329.0001 | 04054839116216 |
Documentation
H₂S Fluorescent Probe, P3 - Calbiochem SDS
Title |
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References
Reference overview |
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Singha, S., et al. 2015. Anal. Chem. 87, 1188. |
Data Sheet | ||||||||||||||||||||||||||
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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